Epidermal Growth Factor Receptor Inhibitor Database


Activity against kinases
Molecule Id: EGIN0000003
S.No. Kinase Mutant IC50 Ki Kd Enz. inhib. (%) Inhib. Conc. Cellular IC50 Cell line Growth Factor
1VEGFR2 ->10000 nM-------
2ß-InsRK->100000 nM-------
3HGFR->20000 nM-------
4c-SRC->20000 nM-------
5VEGFR-2->100000 nM-------
6HN5-120 nM-------
7BT474-80 nM-------
8N87-80 nM-------
9pIGF-1R->10000 nM-------
10pIGF1R->30000 nM-------
11HDAC->100000 nM-------
12rHDAC1->10000 nM-------
13rHDAC3->10000 nM-------
14rHDAC6->10000 nM-------
15rHDAC8->10000 nM-------
16H3K->30000 nM-------
17PDGF-Rß-8500 nM-------
18InsR-17000 nM-------
19Abl1-23000 nM-------
20CDK2-11000 nM-------
21PKA->100000 nM-------
22PlK1->100000 nM-------
23BT474-100 nM-------
24BT474-100 nM-------
25N87-90 nM-------
26VEGFR2->10000 nM-------