Compound Classes Description of EGFRIndb

Epidermal Growth Factor Receptor Inhibitor Database

Compound Class
S.No.	Class	Sub-Class	No of Compounds
1.	Azepine	Diazepine	12
		Diazepinone	1
		Benzoxazepine	35
		Oxazepine	20
		Thiazepine	21
2.	Flavone	Isoflavone	6
		Homo-isoflavonoids	16
		Amino-flavone	16
3.	Furan	Benzo-furan	2
3.	Furan	Benzo-furanone	5
4	Hydantoin	Pseudo-thio-hydantoin	1
		Benzylidene-hydantoin	5
		Methylidene-hydantoin	2
5.	Imidazole	Nitro-imidazole	6
		Pyrimidinyl-imidazole	3
		Imidazole	5
		Benzimidazole	4
6.	Indole	Diselenobis-indole	13
		Dithiobis-indole	115
		Pyrimido-indole	19
		Thioxo-indole	14
		Indole	28
		Indolinone	115
		Indolizine	19
		Indolone	16
		Isoindolone	2
		Isoindole-dione	4
7.	Naphthalene	Naphthalene derivative	3
		Naphthylurea	1
		Naphthyridine	17
8.	Oxazole	Pyridinyl-oxazole	1
		Oxazole	1
		Thiazole	1
		Thiazolidinone	24
		Triazole	5
9.	Phenone	Acrylo-phenone	21
9.	Phenone	Benzo-phenone	1
10.	Purine	Purine	30
11.	Pyrazole	Amino-pyrazole	1
		Dihydroindeno-pyrazole	3
		Pyrrolo-pyrazole	3
		Thieno-pyrazole	1
		Pyrazole	2
12	Pyridine	Diamino-pyridine	3
		Imidazo-pyridine	4
		Pyrazine-Pyridine	4
		Pyrazolo-pyridine	1
		Pyrrolo-pyridine	1
		Thieno-pyridine	18
		Triazine-pyridine	1
		Benzimidazole-pyridone	2
13.	Pyrimidine	Pyrido-pyrimidine	257
		Pyrazolo-pyrimidine	264
		Pyrimidine	254
		Pyrrolo-pyrimidine	176
		Thieno-pyrimidine	109
		Anilino-pyrimidine	55
		Pyrrolo-pyrimidinone	25
		Benzo-thieno-pyrimidine	23
		Thiazolo-pyrimidine	22
		Pyrimido-Pyrimidine	42
		Anilino-pyrido-pyrimidine	13
		Pyrido-thieno-pyrimidine	2
		Pyrrolo-pyrimidone	2
		Benzo-furano-pyrimidine	1
		Thiazolo-thieno-pyrimidine	1
		Imidazole-pyrimidine	1
		Pyridinyl-Pyrimidine	1
		Pyrimidinone	1
14.	Quinazoline	Anilino-quinazoline	857
14.	Quinazoline	Quinazoline	182
15.	Quinoline	Anilino-quinoline	258
		Iso-quinoline	13
		Pyndinyl-quinoline	4
		Quinoline	51
		Iso-quinolinone	2
16.	Quinone	Naphtho-furo-quinone	16
16.	Quinone	Quinone	5
17.	Thiazole	Amino-thiazole	5
		Benzo-thiazole	55
		Carboxamido-thiazole	1
		Imidazo-thiazole	21
		Thioaryl-thiazole	1
		Oxadiazole	1
18.	Triazine	Benzo-triazine	2
		Pyridinyl-triazine	1
		Pyrrolo-triazine	129
		Triazene	7
		Triazine	29
19.	Urea	Pyrazole-thio-urea	46
		Phenyl-urea	18
		Pyrazole-urea	1
		Thiourea	18
20.	Tyrphostin	Tyrphostin	173
21.	Salicylate	Amino-salicylate	88
22.	Other
		Benzylidene	27
		Salicylanilide	32
		Hydroxybiphenyl	26
		Phthalimide	26
		Sulfonyl-benzoyl-Nitrostyrene	24
		Dianilino-phthalimide	24
		Benzoic nitrogen mustard derivative	20
		Chrysin	20
		Benzodioxane	19
		Cinnamic acid metronidazole ester	19
		Diphenyl-amine	32
		Quercetin	16
		Biaryl	13
		Azaspiro-octane	12
		Cinnamide	5
		Benzamide	10
		Carboline	13
		Alternaria(Extract)	8
		Benzamidine	8
		Pyrrolo-pyridazine	8
		Anthraquinone	7
		Indolylmaleimide	4
		Imidazo-pyrazine	5
		Pyrrole-dione	5
		Chalcone	2
		Flavopiridol	3
		Methanone	4
		Cisplatin	1
		Pyridine	3
		Anthracycline	1
		Anthranilamide	2
		Benzo-diazole	2
		Betaenone	2
		Phthalazine	2
		Pyridine-aceto-nitrile	1
		Quinoxaline	2
		Steroid	2
		Amido-hetero-aryl	1
		Benzoxazole	1
		Bisindolylmaleimide	2
		Butyrolactone	1
		Cinnoline	1
		Imidazo-quinoxaline	1
		Indirubin	1
		Propenamide	1
		Pyrazoleamide	1
		Pyridinone	1
		Indazole	9
		Nicotinamide	24
		Piperidine	1
		Pyrazolyl-thiazolinone	36
		Unknown	46

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