Welcome to CellPPD-Mod
CellPPD-Mod is an in silico method, which is developed to predict and design efficient modified cell penetrating peptides (CellPPD-Mods). The main dataset used in this method consists of 732 experimentally validated Modidied CPPs.
Major Features include:
(1) Desing Peptide: This module allows user to generate all possible single mutant analogues of their submitted peptides including modifications like non-natural residues, terminal modifications (Acetylation/Amidation), Cyclization (N-C, disulfide bridges).
(2) Multiple Peptides: This module of CellPPD-Mod allows user to predict number of modified CPPs in peptides submitted by the user.
(3) Protein Scanning: This module generates all possible overlapping peptides and their single mutant analogues of protein submitted by the user. It also predicts whether overlapping peptide/analogue is modified CPP or not.
(4) Motif Scan: Allows user to identify modified CPP motif in their sequences.
One of the major features of server is that it also calculates various physicochemical properties. Peptide analogues can be displayed in sorting order based upon desired properties