Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
TP53ACPGRDRRELUNG276p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del10.11HCC1833N000N
TP53AKTCPVQLCCENTRAL_NERVOUS_SYSTEM138p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del10.11YKG1N100N
TP53ALIRVEGNLLIVER189p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del10.11JHH5Y12160N
TP53CPGRDRRENLUNG277p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del20.11HCC1833N300N
TP53CPVQLCTPPCENTRAL_NERVOUS_SYSTEM141p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del40.11YKG1N000N
TP53CTPPPGTRVCENTRAL_NERVOUS_SYSTEM146p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del10.11YKG1Y290N
TP53CTTIYNYMCHAEMATOPOIETIC_AND_LYMPHOID_TISSUE229p.H233delc.697_699delCACIn_Frame_Del30.11MEG01N100N
TP53DCTTIYNYMHAEMATOPOIETIC_AND_LYMPHOID_TISSUE228p.H233delc.697_699delCACIn_Frame_Del40.11MEG01Y290Y
TP53DDRNTFRHVBONE207p.S215delc.643_645delAGTIn_Frame_Del10.11MHHES1Y4100Y
TP53DGLALIRVELIVER186p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del40.11JHH5N000N
TP53DRNTFRHVVBONE208p.S215delc.643_645delAGTIn_Frame_Del10.11MHHES1Y490N
TP53DRRENLRKKLUNG281p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del30.11HCC1833Y190N
TP53DRRTENLRKBONE281p.EE286delc.856_861delGAAGAGIn_Frame_Del40.11CAL78N200N
TP53DSDGLALIRLIVER184p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del30.11JHH5N400N
TP53EVGRCPHHEUPPER_AERODIGESTIVE_TRACT171p.173_174VR>Gc.518_520delTGAIn_Frame_Del20.11BICR31N000N
TP53FRHVVVPYEBONE212p.S215delc.643_645delAGTIn_Frame_Del30.11MHHES1N3014N
TP53GLALIRVEGLIVER187p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del30.11JHH5N000N
TP53GRCPHHERCUPPER_AERODIGESTIVE_TRACT173p.173_174VR>Gc.518_520delTGAIn_Frame_Del10.11BICR31N200N
TP53GRDRRENLRLUNG279p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del40.11HCC1833Y390N
TP53GRDRRTENLBONE279p.EE286delc.856_861delGAAGAGIn_Frame_Del20.11CAL78Y6100N
TP53GSDCTTIYNHAEMATOPOIETIC_AND_LYMPHOID_TISSUE226p.H233delc.697_699delCACIn_Frame_Del20.11MEG01N100Y
TP53HMTEVGRCPUPPER_AERODIGESTIVE_TRACT168p.173_174VR>Gc.518_520delTGAIn_Frame_Del30.11BICR31N000N
TP53HVVVPYEPPBONE214p.S215delc.643_645delAGTIn_Frame_Del10.11MHHES1N100N
TP53IYNYMCNSSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE232p.H233delc.697_699delCACIn_Frame_Del10.11MEG01N2021N
TP53KTCPVQLCTCENTRAL_NERVOUS_SYSTEM139p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del20.11YKG1N200N
TP53LALIRVEGNLIVER188p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del20.11JHH5N201N
TP53LCTPPPGTRCENTRAL_NERVOUS_SYSTEM145p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del20.11YKG1N300N
TP53MTEVGRCPHUPPER_AERODIGESTIVE_TRACT169p.173_174VR>Gc.518_520delTGAIn_Frame_Del40.11BICR31N100N
TP53NTFRHVVVPBONE210p.S215delc.643_645delAGTIn_Frame_Del20.11MHHES1N000N
TP53PGRDRRENLLUNG278p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del30.11HCC1833N400N
TP53PGRDRRTENBONE278p.EE286delc.856_861delGAAGAGIn_Frame_Del10.11CAL78N000N
TP53PVQLCTPPPCENTRAL_NERVOUS_SYSTEM142p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del50.11YKG1N000N
TP53QHMTEVGRCUPPER_AERODIGESTIVE_TRACT167p.173_174VR>Gc.518_520delTGAIn_Frame_Del20.11BICR31N200N
TP53QLCTPPPGTCENTRAL_NERVOUS_SYSTEM144p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del30.11YKG1N300Y
TP53QSQHMTEVGUPPER_AERODIGESTIVE_TRACT165p.173_174VR>Gc.518_520delTGAIn_Frame_Del10.11BICR31N000N
TP53RDRRENLRKLUNG280p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del30.11HCC1833N000N
TP53RDRRTENLRBONE280p.EE286delc.856_861delGAAGAGIn_Frame_Del30.11CAL78N100N
TP53RENLRKKGELUNG283p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del10.11HCC1833N000N
TP53RHVVVPYEPBONE213p.S215delc.643_645delAGTIn_Frame_Del20.11MHHES1N000N
TP53RNTFRHVVVBONE209p.S215delc.643_645delAGTIn_Frame_Del10.11MHHES1N300N
TP53RRENLRKKGLUNG282p.TEE284delc.850_858delACAGAGGAAIn_Frame_Del20.11HCC1833N100Y
TP53RRTENLRKKBONE282p.EE286delc.856_861delGAAGAGIn_Frame_Del30.11CAL78N200N
TP53RTENLRKKGBONE283p.EE286delc.856_861delGAAGAGIn_Frame_Del20.11CAL78N200N
TP53SDCTTIYNYHAEMATOPOIETIC_AND_LYMPHOID_TISSUE227p.H233delc.697_699delCACIn_Frame_Del30.11MEG01N300N
TP53SDGLALIRVLIVER185p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del40.11JHH5Y490N
TP53SDSDGLALILIVER183p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del20.11JHH5Y390N
TP53SQHMTEVGRUPPER_AERODIGESTIVE_TRACT166p.173_174VR>Gc.518_520delTGAIn_Frame_Del10.11BICR31N500N
TP53TCPVQLCTPCENTRAL_NERVOUS_SYSTEM140p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del30.11YKG1N000N
TP53TENLRKKGEBONE284p.EE286delc.856_861delGAAGAGIn_Frame_Del10.11CAL78N000N
TP53TEVGRCPHHUPPER_AERODIGESTIVE_TRACT170p.173_174VR>Gc.518_520delTGAIn_Frame_Del30.11BICR31N100N
TP53TFRHVVVPYBONE211p.S215delc.643_645delAGTIn_Frame_Del30.11MHHES1Y3110N
TP53TIYNYMCNSHAEMATOPOIETIC_AND_LYMPHOID_TISSUE231p.H233delc.697_699delCACIn_Frame_Del20.11MEG01N000N
TP53TTIYNYMCNHAEMATOPOIETIC_AND_LYMPHOID_TISSUE230p.H233delc.697_699delCACIn_Frame_Del20.11MEG01N200N
TP53VGRCPHHERUPPER_AERODIGESTIVE_TRACT172p.173_174VR>Gc.518_520delTGAIn_Frame_Del10.11BICR31N102N
TP53VGSDCTTIYHAEMATOPOIETIC_AND_LYMPHOID_TISSUE225p.H233delc.697_699delCACIn_Frame_Del10.11MEG01N7011Y
TP53VQLCTPPPGCENTRAL_NERVOUS_SYSTEM143p.146_149WVDS>Cc.438_446delGGTTGATTCIn_Frame_Del40.11YKG1N008Y
TP53CSDSDGLALLIVER182p.PPQH190delc.569_580delCTCCTCAGCATCIn_Frame_Del10.22JHH5N800N
TP53FRHSVVPYELUNG212p.V218delc.652_654delGTGIn_Frame_Del30.22HCC827N3017N
TP53FRHSVVPYEENDOMETRIUM212p.V218delc.652_654delGTGIn_Frame_Del30.22RL952N3017N
TP53HSVVPYEPPLUNG214p.V218delc.652_654delGTGIn_Frame_Del20.22HCC827N100Y
TP53HSVVPYEPPENDOMETRIUM214p.V218delc.652_654delGTGIn_Frame_Del20.22RL952N100Y
TP53NTFRHSVVPLUNG210p.V218delc.652_654delGTGIn_Frame_Del10.22HCC827N000N
TP53NTFRHSVVPENDOMETRIUM210p.V218delc.652_654delGTGIn_Frame_Del10.22RL952N000N
TP53RHSVVPYEPLUNG213p.V218delc.652_654delGTGIn_Frame_Del30.22HCC827N000N
TP53RHSVVPYEPENDOMETRIUM213p.V218delc.652_654delGTGIn_Frame_Del30.22RL952N000N
TP53SVVPYEPPELUNG215p.V218delc.652_654delGTGIn_Frame_Del10.22HCC827N000Y
TP53SVVPYEPPEENDOMETRIUM215p.V218delc.652_654delGTGIn_Frame_Del10.22RL952N000Y
TP53TFRHSVVPYLUNG211p.V218delc.652_654delGTGIn_Frame_Del20.22HCC827N300N
TP53TFRHSVVPYENDOMETRIUM211p.V218delc.652_654delGTGIn_Frame_Del20.22RL952N300N