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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SMAD4 | ESLVKKLKD | BREAST | 41 | p.EKK49del | c.145_153delGAGAAAAAA | In_Frame_Del | 1 | 0.11 | HCC1428 | N | 0 | 0 | 0 | N | ||||||||||||
SMAD4 | KKLKDELDS | BREAST | 45 | p.EKK49del | c.145_153delGAGAAAAAA | In_Frame_Del | 2 | 0.11 | HCC1428 | N | 1 | 0 | 0 | N | ||||||||||||
SMAD4 | KLKDELDSL | BREAST | 46 | p.EKK49del | c.145_153delGAGAAAAAA | In_Frame_Del | 2 | 0.11 | HCC1428 | Y | 13 | 16 | 0 | N | ||||||||||||
SMAD4 | LKDELDSLI | BREAST | 47 | p.EKK49del | c.145_153delGAGAAAAAA | In_Frame_Del | 1 | 0.11 | HCC1428 | N | 3 | 0 | 0 | N | ||||||||||||
SMAD4 | LVKKLKDEL | BREAST | 43 | p.EKK49del | c.145_153delGAGAAAAAA | In_Frame_Del | 3 | 0.11 | HCC1428 | N | 7 | 0 | 9 | N | ||||||||||||
SMAD4 | SLVKKLKDE | BREAST | 42 | p.EKK49del | c.145_153delGAGAAAAAA | In_Frame_Del | 2 | 0.11 | HCC1428 | N | 0 | 0 | 0 | N | ||||||||||||
SMAD4 | VKKLKDELD | BREAST | 44 | p.EKK49del | c.145_153delGAGAAAAAA | In_Frame_Del | 3 | 0.11 | HCC1428 | N | 0 | 0 | 0 | N | ||||||||||||