Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MYST4 | ANIGLYEGQ | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1790 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 2 | 0.11 | KMS26 | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | EGQSDFGAG | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1796 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 1 | 0.11 | KMS26 | N | 0 | 0 | 0 | Y | ||||||||||||
| MYST4 | GLYEGQSDF | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1793 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 4 | 0.11 | KMS26 | N | 8 | 0 | 0 | N | ||||||||||||
| MYST4 | IGLYEGQSD | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1792 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 4 | 0.11 | KMS26 | N | 0 | 0 | 2 | N | ||||||||||||
| MYST4 | LYEGQSDFG | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1794 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 3 | 0.11 | KMS26 | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | NANIGLYEG | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1789 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 1 | 0.11 | KMS26 | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | NIGLYEGQS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1791 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 3 | 0.11 | KMS26 | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | SEEEEEEEE | BREAST | 1069 | p.EEED1074del | c.3220_3231delGAGGAGGAGGAC | In_Frame_Del | 1 | 0.11 | BT20 | N | 0 | 0 | 0 | N | ||||||||||||
| MYST4 | YEGQSDFGA | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1795 | p.RM1797del | c.5388_5393delGCGAAT | In_Frame_Del | 2 | 0.11 | KMS26 | N | 8 | 0 | 0 | Y | ||||||||||||
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