Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
FBXW7DEEEEEEEMKIDNEY112p.117_118insEEc.351_352insGAGGAGIn_Frame_Ins20.11OSRC2N600N
FBXW7EEEEEEEMDKIDNEY113p.117_118insEEc.351_352insGAGGAGIn_Frame_Ins10.11OSRC2N000N
FBXW7EEEEEEMDQKIDNEY114p.117_118insEEc.351_352insGAGGAGIn_Frame_Ins10.11OSRC2N000N
FBXW7GSKRRRTPGCENTRAL_NERVOUS_SYSTEM9p.15_16insPc.45_46insCCTIn_Frame_Ins10.11GAMGN100N
FBXW7KRRRTPGGSCENTRAL_NERVOUS_SYSTEM11p.15_16insPc.45_46insCCTIn_Frame_Ins30.11GAMGN200Y
FBXW7PGGSLRGNPCENTRAL_NERVOUS_SYSTEM16p.15_16insPc.45_46insCCTIn_Frame_Ins10.11GAMGN000N
FBXW7RRRTPGGSLCENTRAL_NERVOUS_SYSTEM12p.15_16insPc.45_46insCCTIn_Frame_Ins30.11GAMGN500N
FBXW7RRTPGGSLRCENTRAL_NERVOUS_SYSTEM13p.15_16insPc.45_46insCCTIn_Frame_Ins20.11GAMGY390Y
FBXW7RTPGGSLRGCENTRAL_NERVOUS_SYSTEM14p.15_16insPc.45_46insCCTIn_Frame_Ins20.11GAMGN000N
FBXW7SKRRRTPGGCENTRAL_NERVOUS_SYSTEM10p.15_16insPc.45_46insCCTIn_Frame_Ins20.11GAMGN000N
FBXW7TPGGSLRGNCENTRAL_NERVOUS_SYSTEM15p.15_16insPc.45_46insCCTIn_Frame_Ins20.11GAMGN300N
FBXW7VGSKRRRTPCENTRAL_NERVOUS_SYSTEM8p.15_16insPc.45_46insCCTIn_Frame_Ins10.11GAMGN0014N