Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
TNFAIP3AAPLEAPCLLARGE_INTESTINE662p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON1100N
TNFAIP3AHCVSSSTELARGE_INTESTINE624p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3ALFCSVRPLENDOMETRIUM466p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319Y1690N
TNFAIP3APCLKDTARLARGE_INTESTINE667p.F623fsc.1867_1867delTFrame_Shift_Del40.11LOVOY390N
TNFAIP3APLEAPCLKLARGE_INTESTINE663p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON300N
TNFAIP3ARSVSLKLRLARGE_INTESTINE674p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON300N
TNFAIP3AWGGNAAPLLARGE_INTESTINE657p.F623fsc.1867_1867delTFrame_Shift_Del40.11LOVON600N
TNFAIP3CLKDTARSVLARGE_INTESTINE669p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVOY490N
TNFAIP3CVSSSTEKTLARGE_INTESTINE626p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON000N
TNFAIP3DFMRPKGQKLARGE_INTESTINE685p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON000N
TNFAIP3DTARSVSLKLARGE_INTESTINE672p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVOY3110N
TNFAIP3EAPCLKDTALARGE_INTESTINE666p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON200N
TNFAIP3EESTGGLIRENDOMETRIUM451p.G455fsc.1363_1363delGFrame_Shift_Del30.11MFE319N000N
TNFAIP3EKTNILLLPLARGE_INTESTINE632p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3ENKGFAHCVLARGE_INTESTINE619p.F623fsc.1867_1867delTFrame_Shift_Del40.11LOVON100N
TNFAIP3ESTGGLIRPENDOMETRIUM452p.G455fsc.1363_1363delGFrame_Shift_Del40.11MFE319N000N
TNFAIP3FAHCVSSSTLARGE_INTESTINE623p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON600N
TNFAIP3FMRPKGQKSLARGE_INTESTINE686p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON200N
TNFAIP3FRAWGGNAALARGE_INTESTINE655p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVOY5109N
TNFAIP3GFAHCVSSSLARGE_INTESTINE622p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON000N
TNFAIP3GGLIRPHRQENDOMETRIUM455p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319N000N
TNFAIP3GGNAAPLEALARGE_INTESTINE659p.F623fsc.1867_1867delTFrame_Shift_Del40.11LOVON000N
TNFAIP3GKSVPQRPGLARGE_INTESTINE642p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3GLIRPHRQHENDOMETRIUM456p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319N000N
TNFAIP3GNAAPLEAPLARGE_INTESTINE660p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3GSRTPFRAWLARGE_INTESTINE650p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVOY390N
TNFAIP3HCVSSSTEKLARGE_INTESTINE625p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON200N
TNFAIP3HPALFCSVRENDOMETRIUM464p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319Y490N
TNFAIP3HRQHPALFCENDOMETRIUM461p.G455fsc.1363_1363delGFrame_Shift_Del50.11MFE319N200N
TNFAIP3ILLLPQGKSLARGE_INTESTINE636p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON0011N
TNFAIP3IRDFMRPKGLARGE_INTESTINE683p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON105Y
TNFAIP3IRPHRQHPAENDOMETRIUM458p.G455fsc.1363_1363delGFrame_Shift_Del50.11MFE319N6018Y
TNFAIP3KDTARSVSLLARGE_INTESTINE671p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON600N
TNFAIP3KGFAHCVSSLARGE_INTESTINE621p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON100N
TNFAIP3KLRIRDFMRLARGE_INTESTINE680p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVOY8100Y
TNFAIP3KSVPQRPGSLARGE_INTESTINE643p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON100N
TNFAIP3KTNILLLPQLARGE_INTESTINE633p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON200N
TNFAIP3LEAPCLKDTLARGE_INTESTINE665p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON500N
TNFAIP3LFCSVRPLPENDOMETRIUM467p.G455fsc.1363_1363delGFrame_Shift_Del50.11MFE319N000N
TNFAIP3LIRPHRQHPENDOMETRIUM457p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319N000N
TNFAIP3LKDTARSVSLARGE_INTESTINE670p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON100N
TNFAIP3LKLRIRDFMLARGE_INTESTINE679p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON708Y
TNFAIP3LLLPQGKSVLARGE_INTESTINE637p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON700N
TNFAIP3LLPQGKSVPLARGE_INTESTINE638p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3LPQGKSVPQLARGE_INTESTINE639p.F623fsc.1867_1867delTFrame_Shift_Del40.11LOVON200Y
TNFAIP3LRIRDFMRPLARGE_INTESTINE681p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON109N
TNFAIP3MRPKGQKSNLARGE_INTESTINE687p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON206N
TNFAIP3NAAPLEAPCLARGE_INTESTINE661p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON200N
TNFAIP3NILLLPQGKLARGE_INTESTINE635p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON400N
TNFAIP3NKGFAHCVSLARGE_INTESTINE620p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON100N
TNFAIP3PALFCSVRPENDOMETRIUM465p.G455fsc.1363_1363delGFrame_Shift_Del50.11MFE319N000N
TNFAIP3PCLKDTARSLARGE_INTESTINE668p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3PENKGFAHCLARGE_INTESTINE618p.F623fsc.1867_1867delTFrame_Shift_Del30.11LOVON000N
TNFAIP3PFRAWGGNALARGE_INTESTINE654p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3PGSRTPFRALARGE_INTESTINE649p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3PHRQHPALFENDOMETRIUM460p.G455fsc.1363_1363delGFrame_Shift_Del50.11MFE319N000N
TNFAIP3PLEAPCLKDLARGE_INTESTINE664p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON000N
TNFAIP3PQGKSVPQRLARGE_INTESTINE640p.F623fsc.1867_1867delTFrame_Shift_Del40.11LOVON100N
TNFAIP3PQRPGSRTPLARGE_INTESTINE646p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000Y
TNFAIP3QGKSVPQRPLARGE_INTESTINE641p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3QHPALFCSVENDOMETRIUM463p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319N400N
TNFAIP3QRPGSRTPFLARGE_INTESTINE647p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON500N
TNFAIP3RAWGGNAAPLARGE_INTESTINE656p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3RDFMRPKGQLARGE_INTESTINE684p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON000Y
TNFAIP3RIRDFMRPKLARGE_INTESTINE682p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVOY2100Y
TNFAIP3RPGSRTPFRLARGE_INTESTINE648p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON400N
TNFAIP3RPHRQHPALENDOMETRIUM459p.G455fsc.1363_1363delGFrame_Shift_Del50.11MFE319Y17110Y
TNFAIP3RQHPALFCSENDOMETRIUM462p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319N200N
TNFAIP3RSVSLKLRILARGE_INTESTINE675p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON800N
TNFAIP3RTPFRAWGGLARGE_INTESTINE652p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3SLKLRIRDFLARGE_INTESTINE678p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVOY490N
TNFAIP3SRTPFRAWGLARGE_INTESTINE651p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVOY190N
TNFAIP3SSSTEKTNILARGE_INTESTINE628p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON400N
TNFAIP3SSTEKTNILLARGE_INTESTINE629p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON1000N
TNFAIP3STEKTNILLLARGE_INTESTINE630p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVOY7110N
TNFAIP3STGGLIRPHENDOMETRIUM453p.G455fsc.1363_1363delGFrame_Shift_Del50.11MFE319N000N
TNFAIP3SVPQRPGSRLARGE_INTESTINE644p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVOY5100N
TNFAIP3SVSLKLRIRLARGE_INTESTINE676p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVOY490N
TNFAIP3TARSVSLKLLARGE_INTESTINE673p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON1000N
TNFAIP3TEKTNILLLLARGE_INTESTINE631p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVOY9100N
TNFAIP3TGGLIRPHRENDOMETRIUM454p.G455fsc.1363_1363delGFrame_Shift_Del60.11MFE319N100N
TNFAIP3TNILLLPQGLARGE_INTESTINE634p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON000N
TNFAIP3TPFRAWGGNLARGE_INTESTINE653p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON500N
TNFAIP3VPQRPGSRTLARGE_INTESTINE645p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON500N
TNFAIP3VSLKLRIRDLARGE_INTESTINE677p.F623fsc.1867_1867delTFrame_Shift_Del50.11LOVON004N
TNFAIP3VSSSTEKTNLARGE_INTESTINE627p.F623fsc.1867_1867delTFrame_Shift_Del60.11LOVON000N
TNFAIP3WGGNAAPLELARGE_INTESTINE658p.F623fsc.1867_1867delTFrame_Shift_Del40.11LOVON200N
TNFAIP3ALCGAENERHAEMATOPOIETIC_AND_LYMPHOID_TISSUE94p.L92fsc.274_275insTTGTGGCGCTFrame_Shift_Ins50.11SUPHD1N500N
TNFAIP3KLVALCGAEHAEMATOPOIETIC_AND_LYMPHOID_TISSUE91p.L92fsc.274_275insTTGTGGCGCTFrame_Shift_Ins40.11SUPHD1N000N
TNFAIP3LVALCGAENHAEMATOPOIETIC_AND_LYMPHOID_TISSUE92p.L92fsc.274_275insTTGTGGCGCTFrame_Shift_Ins50.11SUPHD1N003Y
TNFAIP3RKLVALCGAHAEMATOPOIETIC_AND_LYMPHOID_TISSUE90p.L92fsc.274_275insTTGTGGCGCTFrame_Shift_Ins30.11SUPHD1N300N
TNFAIP3VALCGAENEHAEMATOPOIETIC_AND_LYMPHOID_TISSUE93p.L92fsc.274_275insTTGTGGCGCTFrame_Shift_Ins50.11SUPHD1N000N