Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
RETAPPHRGVRQLUNG800p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N000Y
RETDGPAPPHRGLUNG797p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N100Y
RETGPAPPHRGVLUNG798p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347Y13120Y
RETGVRQIRLPALUNG805p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N200N
RETHRGVRQIRLLUNG803p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347Y7100N
RETPAPPHRGVRLUNG799p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N000Y
RETPHRGVRQIRLUNG802p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N000N
RETPPHRGVRQILUNG801p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347Y7130N
RETPPSSPPFHMLARGE_INTESTINE1048p.A1046fsc.3136_3137insCFrame_Shift_Ins60.11LS411NN500N
RETPREPQSGAWLUNG817p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N100N
RETQLQLPGPPGLUNG834p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N000N
RETREPQSGAWLLUNG818p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347Y12100N
RETRGVRQIRLPLUNG804p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N000N
RETRQIRLPAGLLUNG807p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N1600N
RETVRQIRLPAGLUNG806p.G798fsc.2393_2394insCFrame_Shift_Ins60.11NCIH2347N1010N