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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RET | APPHRGVRQ | LUNG | 800 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 0 | 0 | 0 | Y | ||||||||||||
RET | DGPAPPHRG | LUNG | 797 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 1 | 0 | 0 | Y | ||||||||||||
RET | GPAPPHRGV | LUNG | 798 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | Y | 13 | 12 | 0 | Y | ||||||||||||
RET | GVRQIRLPA | LUNG | 805 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 2 | 0 | 0 | N | ||||||||||||
RET | HRGVRQIRL | LUNG | 803 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | Y | 7 | 10 | 0 | N | ||||||||||||
RET | PAPPHRGVR | LUNG | 799 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 0 | 0 | 0 | Y | ||||||||||||
RET | PHRGVRQIR | LUNG | 802 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 0 | 0 | 0 | N | ||||||||||||
RET | PPHRGVRQI | LUNG | 801 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | Y | 7 | 13 | 0 | N | ||||||||||||
RET | PPSSPPFHM | LARGE_INTESTINE | 1048 | p.A1046fs | c.3136_3137insC | Frame_Shift_Ins | 6 | 0.11 | LS411N | N | 5 | 0 | 0 | N | ||||||||||||
RET | PREPQSGAW | LUNG | 817 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 1 | 0 | 0 | N | ||||||||||||
RET | QLQLPGPPG | LUNG | 834 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 0 | 0 | 0 | N | ||||||||||||
RET | REPQSGAWL | LUNG | 818 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | Y | 12 | 10 | 0 | N | ||||||||||||
RET | RGVRQIRLP | LUNG | 804 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 0 | 0 | 0 | N | ||||||||||||
RET | RQIRLPAGL | LUNG | 807 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 16 | 0 | 0 | N | ||||||||||||
RET | VRQIRLPAG | LUNG | 806 | p.G798fs | c.2393_2394insC | Frame_Shift_Ins | 6 | 0.11 | NCIH2347 | N | 1 | 0 | 10 | N | ||||||||||||