Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDGFRA | ASKIVSTVI | LARGE_INTESTINE | 810 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 4 | 0.11 | HT115 | Y | 6 | 16 | 0 | N | ||||||||||||
| PDGFRA | ATSSWHKEK | LARGE_INTESTINE | 822 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 3 | 0 | 0 | N | ||||||||||||
| PDGFRA | CSLCTSRND | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 125 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 6 | 0.11 | KASUMI1 | N | 1 | 0 | 0 | N | ||||||||||||
| PDGFRA | CTSRNDGLF | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 128 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 5 | 0.11 | KASUMI1 | N | 2 | 0 | 0 | N | ||||||||||||
| PDGFRA | DGLFSHRGG | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 133 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 5 | 0.11 | KASUMI1 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | DPCSLCTSR | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 123 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 6 | 0.11 | KASUMI1 | N | 3 | 0 | 0 | N | ||||||||||||
| PDGFRA | EFLASKIVS | LARGE_INTESTINE | 807 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 3 | 0.11 | HT115 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | FLASKIVST | LARGE_INTESTINE | 808 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 4 | 0.11 | HT115 | N | 6 | 0 | 1 | N | ||||||||||||
| PDGFRA | IVSTVIWLL | LARGE_INTESTINE | 813 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 4 | 0.11 | HT115 | Y | 11 | 9 | 4 | N | ||||||||||||
| PDGFRA | IWLLATSSW | LARGE_INTESTINE | 818 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 2 | 0 | 5 | N | ||||||||||||
| PDGFRA | IYVPDPCSL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 119 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 3 | 0.11 | KASUMI1 | Y | 8 | 9 | 0 | N | ||||||||||||
| PDGFRA | KIVSTVIWL | LARGE_INTESTINE | 812 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 4 | 0.11 | HT115 | Y | 18 | 9 | 0 | N | ||||||||||||
| PDGFRA | LASKIVSTV | LARGE_INTESTINE | 809 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 8 | 0 | 2 | N | ||||||||||||
| PDGFRA | LATSSWHKE | LARGE_INTESTINE | 821 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | LCTSRNDGL | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 127 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 6 | 0.11 | KASUMI1 | N | 8 | 0 | 0 | Y | ||||||||||||
| PDGFRA | LLATSSWHK | LARGE_INTESTINE | 820 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 6 | 0 | 3 | N | ||||||||||||
| PDGFRA | MEFLASKIV | LARGE_INTESTINE | 806 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 2 | 0.11 | HT115 | N | 12 | 0 | 2 | N | ||||||||||||
| PDGFRA | NDGLFSHRG | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 132 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 5 | 0.11 | KASUMI1 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | PCSLCTSRN | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 124 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 6 | 0.11 | KASUMI1 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | PDPCSLCTS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 122 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 6 | 0.11 | KASUMI1 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | RNDGLFSHR | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 131 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 5 | 0.11 | KASUMI1 | Y | 4 | 11 | 0 | N | ||||||||||||
| PDGFRA | SKIVSTVIW | LARGE_INTESTINE | 811 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 3 | 0.11 | HT115 | N | 1 | 0 | 0 | N | ||||||||||||
| PDGFRA | SLCTSRNDG | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 126 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 6 | 0.11 | KASUMI1 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | SRNDGLFSH | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 130 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 5 | 0.11 | KASUMI1 | Y | 2 | 9 | 0 | N | ||||||||||||
| PDGFRA | STVIWLLAT | LARGE_INTESTINE | 815 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 1 | 0 | 0 | N | ||||||||||||
| PDGFRA | TSRNDGLFS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 129 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 5 | 0.11 | KASUMI1 | N | 1 | 0 | 0 | N | ||||||||||||
| PDGFRA | TSSWHKEKL | LARGE_INTESTINE | 823 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | Y | 7 | 10 | 0 | N | ||||||||||||
| PDGFRA | TVIWLLATS | LARGE_INTESTINE | 816 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 4 | 0.11 | HT115 | N | 0 | 0 | 0 | N | ||||||||||||
| PDGFRA | VIWLLATSS | LARGE_INTESTINE | 817 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 4 | 0.11 | HT115 | N | 0 | 0 | 9 | N | ||||||||||||
| PDGFRA | VPDPCSLCT | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 121 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 5 | 0.11 | KASUMI1 | N | 6 | 0 | 0 | N | ||||||||||||
| PDGFRA | VSTVIWLLA | LARGE_INTESTINE | 814 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 3 | 0 | 0 | N | ||||||||||||
| PDGFRA | WLLATSSWH | LARGE_INTESTINE | 819 | p.S811fs | c.2433_2433delA | Frame_Shift_Del | 5 | 0.11 | HT115 | N | 4 | 0 | 14 | N | ||||||||||||
| PDGFRA | YIYVPDPCS | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 118 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 2 | 0.11 | KASUMI1 | N | 2 | 0 | 0 | N | ||||||||||||
| PDGFRA | YVPDPCSLC | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 120 | p.T124fs | c.372_373delAG | Frame_Shift_Del | 4 | 0.11 | KASUMI1 | N | 5 | 0 | 13 | N | ||||||||||||
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