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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
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NRAS | ALNPANPEP | LUNG | 18 | p.T20fs | c.59_60delCA | Frame_Shift_Del | 6 | 0.11 | NCIH1048 | N | 0 | 0 | 0 | N | ||||||||||||
NRAS | KSALNPANP | LUNG | 16 | p.T20fs | c.59_60delCA | Frame_Shift_Del | 5 | 0.11 | NCIH1048 | N | 0 | 0 | 0 | N | ||||||||||||
NRAS | LNPANPEPL | LUNG | 19 | p.T20fs | c.59_60delCA | Frame_Shift_Del | 6 | 0.11 | NCIH1048 | N | 8 | 0 | 1 | Y | ||||||||||||
NRAS | NPANPEPLC | LUNG | 20 | p.T20fs | c.59_60delCA | Frame_Shift_Del | 7 | 0.11 | NCIH1048 | N | 4 | 0 | 0 | N | ||||||||||||
NRAS | PANPEPLCR | LUNG | 21 | p.T20fs | c.59_60delCA | Frame_Shift_Del | 7 | 0.11 | NCIH1048 | N | 0 | 0 | 0 | N | ||||||||||||
NRAS | SALNPANPE | LUNG | 17 | p.T20fs | c.59_60delCA | Frame_Shift_Del | 6 | 0.11 | NCIH1048 | N | 0 | 0 | 0 | N | ||||||||||||