Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MYLK | AHLVPLTFG | STOMACH | 1336 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | APRHLRRQQ | ENDOMETRIUM | 1227 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 2 | 0 | 0 | N | ||||||||||||
| MYLK | AQESQWSCL | ENDOMETRIUM | 1250 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 6 | 0 | 0 | N | ||||||||||||
| MYLK | CPLRSSSSL | ENDOMETRIUM | 1236 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 18 | 0 | 0 | N | ||||||||||||
| MYLK | DKPDPQLAH | STOMACH | 1329 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 4 | 0.11 | 2313287 | N | 1 | 0 | 0 | N | ||||||||||||
| MYLK | DPQLAHLVP | STOMACH | 1332 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | ESQWSCLAK | ENDOMETRIUM | 1252 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 3 | 0 | 0 | N | ||||||||||||
| MYLK | HLRRQQCPL | ENDOMETRIUM | 1230 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 8 | 0 | 0 | N | ||||||||||||
| MYLK | HLVPLTFGA | STOMACH | 1337 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 4 | 0 | 0 | N | ||||||||||||
| MYLK | KKPAPRHLR | ENDOMETRIUM | 1224 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 4 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| MYLK | KPAPRHLRR | ENDOMETRIUM | 1225 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 6 | 11 | 0 | N | ||||||||||||
| MYLK | KPDPQLAHL | STOMACH | 1330 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | Y | 20 | 10 | 0 | N | ||||||||||||
| MYLK | LAHLVPLTF | STOMACH | 1335 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 7 | 0 | 8 | N | ||||||||||||
| MYLK | LRRQQCPLR | ENDOMETRIUM | 1231 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 3 | 0 | 16 | N | ||||||||||||
| MYLK | LRSSSSLRT | ENDOMETRIUM | 1238 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 2 | 0 | 18 | Y | ||||||||||||
| MYLK | LRTRRYAQE | ENDOMETRIUM | 1244 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 1 | 0 | 3 | N | ||||||||||||
| MYLK | LVPLTFGAP | STOMACH | 1338 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | PAPRHLRRQ | ENDOMETRIUM | 1226 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | PDPQLAHLV | STOMACH | 1331 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 1 | 0 | 0 | N | ||||||||||||
| MYLK | PLRSSSSLR | ENDOMETRIUM | 1237 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 0 | Y | ||||||||||||
| MYLK | PQLAHLVPL | STOMACH | 1333 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 5 | 0 | 0 | N | ||||||||||||
| MYLK | PRHLRRQQC | ENDOMETRIUM | 1228 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 2 | 0 | 0 | N | ||||||||||||
| MYLK | QCPLRSSSS | ENDOMETRIUM | 1235 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| MYLK | QESQWSCLA | ENDOMETRIUM | 1251 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 6 | 0 | 0 | N | ||||||||||||
| MYLK | QLAHLVPLT | STOMACH | 1334 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 3 | 0 | 0 | N | ||||||||||||
| MYLK | QQCPLRSSS | ENDOMETRIUM | 1234 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | RHLRRQQCP | ENDOMETRIUM | 1229 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | RQQCPLRSS | ENDOMETRIUM | 1233 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | RRQQCPLRS | ENDOMETRIUM | 1232 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 2 | 0 | 0 | N | ||||||||||||
| MYLK | RRYAQESQW | ENDOMETRIUM | 1247 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 4 | 0 | 0 | N | ||||||||||||
| MYLK | RSSSSLRTR | ENDOMETRIUM | 1239 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 3 | 0 | 0 | Y | ||||||||||||
| MYLK | RTRRYAQES | ENDOMETRIUM | 1245 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| MYLK | RYAQESQWS | ENDOMETRIUM | 1248 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| MYLK | SLRTRRYAQ | ENDOMETRIUM | 1243 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 1 | 15 | 0 | N | ||||||||||||
| MYLK | SSLRTRRYA | ENDOMETRIUM | 1242 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 2 | 9 | 0 | N | ||||||||||||
| MYLK | SSSLRTRRY | ENDOMETRIUM | 1241 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 4 | 0.11 | HEC108 | Y | 5 | 12 | 0 | Y | ||||||||||||
| MYLK | SSSSLRTRR | ENDOMETRIUM | 1240 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | Y | 3 | 9 | 0 | Y | ||||||||||||
| MYLK | TRRYAQESQ | ENDOMETRIUM | 1246 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 5 | 0.11 | HEC108 | N | 1 | 0 | 0 | N | ||||||||||||
| MYLK | VPLTFGAPH | STOMACH | 1339 | p.P1334fs | c.4001_4001delC | Frame_Shift_Del | 5 | 0.11 | 2313287 | N | 2 | 0 | 0 | Y | ||||||||||||
| MYLK | YAQESQWSC | ENDOMETRIUM | 1249 | p.P1228fs | c.3684_3684delC | Frame_Shift_Del | 6 | 0.11 | HEC108 | N | 7 | 0 | 0 | N | ||||||||||||
| MYLK | AAMPPSDHP | ENDOMETRIUM | 1234 | p.P1238fs | c.3713_3714insC | Frame_Shift_Ins | 4 | 0.11 | HEC1A | N | 0 | 0 | 0 | N | ||||||||||||
| MYLK | AMPPSDHPV | ENDOMETRIUM | 1235 | p.P1238fs | c.3713_3714insC | Frame_Shift_Ins | 5 | 0.11 | HEC1A | N | 5 | 0 | 0 | Y | ||||||||||||
| MYLK | MPPSDHPVP | ENDOMETRIUM | 1236 | p.P1238fs | c.3713_3714insC | Frame_Shift_Ins | 5 | 0.11 | HEC1A | N | 2 | 0 | 0 | Y | ||||||||||||
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