Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
Browse Results ... |
The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MSH6 | AVLMFYCAW | URINARY_TRACT | 1055 | p.L1057fs | c.3171_3171delG | Frame_Shift_Del | 6 | 0.11 | 639V | Y | 1 | 9 | 0 | N | ||||||||||||
| MSH6 | AWLTIVEGV | URINARY_TRACT | 1062 | p.L1057fs | c.3171_3171delG | Frame_Shift_Del | 6 | 0.11 | 639V | N | 4 | 0 | 0 | N | ||||||||||||
| MSH6 | CAWLTIVEG | URINARY_TRACT | 1061 | p.L1057fs | c.3171_3171delG | Frame_Shift_Del | 6 | 0.11 | 639V | N | 0 | 0 | 0 | N | ||||||||||||
| MSH6 | LMFYCAWLT | URINARY_TRACT | 1057 | p.L1057fs | c.3171_3171delG | Frame_Shift_Del | 6 | 0.11 | 639V | N | 7 | 0 | 5 | N | ||||||||||||
| MSH6 | VLMFYCAWL | URINARY_TRACT | 1056 | p.L1057fs | c.3171_3171delG | Frame_Shift_Del | 6 | 0.11 | 639V | N | 13 | 0 | 25 | N | ||||||||||||
|
||||||||||||||||||||||||||