Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
MSH2APIWEVNQHENDOMETRIUM669p.Y656fsc.1966_1966delTFrame_Shift_Del60.11HEC108N000N
MSH2LAPIWEVNQENDOMETRIUM668p.Y656fsc.1966_1966delTFrame_Shift_Del60.11HEC108N000N
MSH2SLGQSDTNCSOFT_TISSUE788p.T788fsc.2363_2364delCTFrame_Shift_Del60.11SKUT1N200N