Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MLL3 | LINIHHRKN | URINARY_TRACT | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | 639V | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | CMLT1 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LUNG | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | DV90 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LARGE_INTESTINE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | GP2D | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LARGE_INTESTINE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HCT116 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | ENDOMETRIUM | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HEC108 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | ENDOMETRIUM | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HEC151 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | ENDOMETRIUM | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HEC59 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LARGE_INTESTINE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | LOVO | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LARGE_INTESTINE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | LS411N | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | ENDOMETRIUM | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | MFE296 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | ENDOMETRIUM | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | MFE319 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | NALM6 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LUNG | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | NCIH1048 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | REH | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | PANCREAS | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SNU324 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LARGE_INTESTINE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SNU407 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | STOMACH | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SNU520 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | LINIHHRKN | LARGE_INTESTINE | 2807 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SW48 | N | 0 | 0 | 1 | N | ||||||||||||
| MLL3 | SLINIHHRK | URINARY_TRACT | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | 639V | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | CMLT1 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LUNG | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | DV90 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LARGE_INTESTINE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | GP2D | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LARGE_INTESTINE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HCT116 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | ENDOMETRIUM | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HEC108 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | ENDOMETRIUM | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HEC151 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | ENDOMETRIUM | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | HEC59 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LARGE_INTESTINE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | LOVO | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LARGE_INTESTINE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | LS411N | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | ENDOMETRIUM | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | MFE296 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | ENDOMETRIUM | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | MFE319 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | NALM6 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LUNG | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | NCIH1048 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | REH | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | PANCREAS | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SNU324 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LARGE_INTESTINE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SNU407 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | STOMACH | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SNU520 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | SLINIHHRK | LARGE_INTESTINE | 2806 | p.K2797fs | c.8390_8390delA | Frame_Shift_Del | 6 | 2.1 | SW48 | Y | 6 | 13 | 0 | N | ||||||||||||
| MLL3 | MFLRTKLCF | PROSTATE | 4494 | p.F4496fs | c.13488_13488delT | Frame_Shift_Del | 6 | 0.55 | DU145 | N | 6 | 0 | 26 | N | ||||||||||||
| MLL3 | MFLRTKLCF | STOMACH | 4494 | p.F4496fs | c.13488_13488delT | Frame_Shift_Del | 6 | 0.55 | IM95 | N | 6 | 0 | 26 | N | ||||||||||||
| MLL3 | MFLRTKLCF | PROSTATE | 4494 | p.F4496fs | c.13488_13488delT | Frame_Shift_Del | 6 | 0.55 | LNCAPCLONEFGC | N | 6 | 0 | 26 | N | ||||||||||||
| MLL3 | MFLRTKLCF | OVARY | 4494 | p.F4496fs | c.13488_13488delT | Frame_Shift_Del | 6 | 0.55 | OVK18 | N | 6 | 0 | 26 | N | ||||||||||||
| MLL3 | MFLRTKLCF | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 4494 | p.F4496fs | c.13488_13488delT | Frame_Shift_Del | 6 | 0.55 | SEM | N | 6 | 0 | 26 | N | ||||||||||||
| MLL3 | AEYSILCKC | THYROID | 203 | p.M184fs | c.550_551insA | Frame_Shift_Ins | 6 | 0.11 | FTC238 | N | 7 | 0 | 0 | N | ||||||||||||
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