Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
Browse Results ... |
The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MLH1 | AHTFCLLNI | KIDNEY | 725 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | Y | 3 | 13 | 0 | N | ||||||||||||
| MLH1 | CAHTFCLLN | KIDNEY | 724 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 1 | 0 | 0 | N | ||||||||||||
| MLH1 | CLLNISQKM | KIDNEY | 729 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 5 | 0 | 0 | N | ||||||||||||
| MLH1 | CSLLTCLIY | KIDNEY | 741 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 6 | 0 | 0 | N | ||||||||||||
| MLH1 | FCLLNISQK | KIDNEY | 728 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 5 | 0 | 6 | N | ||||||||||||
| MLH1 | GLWNTLSIK | KIDNEY | 714 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 6 | 0 | 0 | N | ||||||||||||
| MLH1 | GSGLWNTLS | KIDNEY | 712 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 0 | 0 | 0 | N | ||||||||||||
| MLH1 | HTFCLLNIS | KIDNEY | 726 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 0 | 0 | 0 | N | ||||||||||||
| MLH1 | ISCSLLTCL | KIDNEY | 739 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 13 | 0 | 0 | N | ||||||||||||
| MLH1 | ISQKMEISC | KIDNEY | 733 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 1 | 0 | 0 | N | ||||||||||||
| MLH1 | KMEISCSLL | KIDNEY | 736 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 12 | 0 | 0 | N | ||||||||||||
| MLH1 | NSGSGLWNT | KIDNEY | 710 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 2 | 0 | 0 | N | ||||||||||||
| MLH1 | PCAHTFCLL | KIDNEY | 723 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 0 | 0 | 0 | N | ||||||||||||
| MLH1 | PNSGSGLWN | KIDNEY | 709 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 0 | 0 | 0 | N | ||||||||||||
| MLH1 | QKMEISCSL | KIDNEY | 735 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 8 | 0 | 0 | N | ||||||||||||
| MLH1 | SCSLLTCLI | KIDNEY | 740 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 2 | 0 | 0 | N | ||||||||||||
| MLH1 | SGSGLWNTL | KIDNEY | 711 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | Y | 11 | 10 | 0 | N | ||||||||||||
| MLH1 | SLLTCLIYT | KIDNEY | 742 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 4 | 0 | 0 | N | ||||||||||||
| MLH1 | SQKMEISCS | KIDNEY | 734 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 1 | 0 | 0 | N | ||||||||||||
| MLH1 | TCLIYTKSL | KIDNEY | 745 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 7 | 0 | 0 | N | ||||||||||||
| MLH1 | TFCLLNISQ | KIDNEY | 727 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 0 | 0 | 0 | N | ||||||||||||
| MLH1 | WNTLSIKPC | KIDNEY | 716 | p.S711fs | c.2132_2132delC | Frame_Shift_Del | 6 | 0.11 | SNU349 | N | 1 | 0 | 8 | N | ||||||||||||
|
||||||||||||||||||||||||||