Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
METASCRLWFLDSTOMACH461p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N000N
METCRLWFLDQDSTOMACH463p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N100N
METEILTPLSMSLARGE_INTESTINE242p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N100N
METFLDQDHQPLSTOMACH467p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N1400N
METGHQRVASCRSTOMACH456p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N100N
METHQRVASCRLSTOMACH457p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N800N
METILTPLSMSMLARGE_INTESTINE243p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N700N
METLDQDHQPLMSTOMACH468p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N500N
METLTPLSMSMPLARGE_INTESTINE244p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N000N
METLWFLDQDHQSTOMACH465p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N000N
METQRVASCRLWSTOMACH458p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N200N
METRLWFLDQDHSTOMACH464p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N200N
METRVASCRLWFSTOMACH459p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74Y5100N
METSCRLWFLDQSTOMACH462p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N000N
METSMPLKATILLARGE_INTESTINE250p.V237fsc.710_710delTFrame_Shift_Del60.11HCT116N1300N
METVASCRLWFLSTOMACH460p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74Y18100N
METWFLDQDHQPSTOMACH466p.G456fsc.1366_1366delGFrame_Shift_Del60.11MKN74N200N