Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
MEN1AARLRCQHPPROSTATE537p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N100N
MEN1ALKVAARLRPROSTATE533p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1Y3100N
MEN1AQPEALKVAPROSTATE529p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N400N
MEN1ARLRCQHPQPROSTATE538p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N100N
MEN1AVSGPPGSLPROSTATE515p.R521fsc.1561_1561delCFrame_Shift_Del30.1122RV1N500N
MEN1CQHPQHHHRPROSTATE542p.R521fsc.1561_1561delCFrame_Shift_Del70.1122RV1N500N
MEN1EALKVAARLPROSTATE532p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N1500N
MEN1GLSLAQPEAPROSTATE525p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N400N
MEN1GPPGSLLGLPROSTATE518p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N2000N
MEN1GSLLGLSLAPROSTATE521p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N300N
MEN1HHHRRRVQCPROSTATE547p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N200N
MEN1HHRRRVQCSPROSTATE548p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N100N
MEN1HPQHHHRRRPROSTATE544p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N400N
MEN1HRRRVQCSLPROSTATE549p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1Y690N
MEN1KVAARLRCQPROSTATE535p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N000N
MEN1LAQPEALKVPROSTATE528p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N600N
MEN1LGLSLAQPEPROSTATE524p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N000N
MEN1LKVAARLRCPROSTATE534p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N1030N
MEN1LLGLSLAQPPROSTATE523p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N000N
MEN1LRCQHPQHHPROSTATE540p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N2022N
MEN1LSLAQPEALPROSTATE526p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N1200N
MEN1PEALKVAARPROSTATE531p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N000N
MEN1PGSLLGLSLPROSTATE520p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N000N
MEN1PPGSLLGLSPROSTATE519p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N000N
MEN1PQHHHRRRVPROSTATE545p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N100N
MEN1QCSLSRVRRPROSTATE554p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1Y390N
MEN1QHHHRRRVQPROSTATE546p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N000N
MEN1QHPQHHHRRPROSTATE543p.R521fsc.1561_1561delCFrame_Shift_Del70.1122RV1N100N
MEN1QPEALKVAAPROSTATE530p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N600N
MEN1RCQHPQHHHPROSTATE541p.R521fsc.1561_1561delCFrame_Shift_Del70.1122RV1N000N
MEN1RLRCQHPQHPROSTATE539p.R521fsc.1561_1561delCFrame_Shift_Del60.1122RV1N100N
MEN1RRRVQCSLSPROSTATE550p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N200N
MEN1RRVQCSLSRPROSTATE551p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N400N
MEN1RVQCSLSRVPROSTATE552p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1Y3110N
MEN1SGPPGSLLGPROSTATE517p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N100N
MEN1SLAQPEALKPROSTATE527p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1Y5160N
MEN1SLLGLSLAQPROSTATE522p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N000N
MEN1VAARLRCQHPROSTATE536p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N006N
MEN1VQCSLSRVRPROSTATE553p.R521fsc.1561_1561delCFrame_Shift_Del50.1122RV1N403N
MEN1VSGPPGSLLPROSTATE516p.R521fsc.1561_1561delCFrame_Shift_Del40.1122RV1N1100N
MEN1ASWDCRWHSPANCREAS523p.R521fsc.1561_1562insCFrame_Shift_Ins60.11T3M4N000N
MEN1AVSGPPPEAPANCREAS515p.R521fsc.1561_1562insCFrame_Shift_Ins30.11T3M4N000N
MEN1DCRWHSPRPPANCREAS526p.R521fsc.1561_1562insCFrame_Shift_Ins60.11T3M4N000N
MEN1EASWDCRWHPANCREAS522p.R521fsc.1561_1562insCFrame_Shift_Ins60.11T3M4N000N
MEN1GPPPEASWDPANCREAS518p.R521fsc.1561_1562insCFrame_Shift_Ins50.11T3M4N000N
MEN1PEASWDCRWPANCREAS521p.R521fsc.1561_1562insCFrame_Shift_Ins60.11T3M4N200N
MEN1PPEASWDCRPANCREAS520p.R521fsc.1561_1562insCFrame_Shift_Ins60.11T3M4N000N
MEN1PPPEASWDCPANCREAS519p.R521fsc.1561_1562insCFrame_Shift_Ins50.11T3M4N000N
MEN1SGPPPEASWPANCREAS517p.R521fsc.1561_1562insCFrame_Shift_Ins50.11T3M4N300N
MEN1SWDCRWHSPPANCREAS524p.R521fsc.1561_1562insCFrame_Shift_Ins60.11T3M4N000N
MEN1VSGPPPEASPANCREAS516p.R521fsc.1561_1562insCFrame_Shift_Ins40.11T3M4N000N
MEN1WDCRWHSPRPANCREAS525p.R521fsc.1561_1562insCFrame_Shift_Ins60.11T3M4N200N