Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
MAP3K1	AAAPAGLRW	BREAST	156	p.R162fs	c.485_485delG	Frame_Shift_Del	3	0.11	MDAMB415	Y	3	12	0	N
MAP3K1	AAPAGLRWR	BREAST	157	p.R162fs	c.485_485delG	Frame_Shift_Del	4	0.11	MDAMB415	N	3	0	0	N
MAP3K1	AGLRWRIKK	BREAST	160	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	Y	0	11	0	N
MAP3K1	APAGLRWRI	BREAST	158	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	Y	13	14	0	N
MAP3K1	CTRWMIVQR	BREAST	173	p.R162fs	c.485_485delG	Frame_Shift_Del	6	0.11	MDAMB415	Y	5	10	0	N
MAP3K1	GCTRWMIVQ	BREAST	172	p.R162fs	c.485_485delG	Frame_Shift_Del	6	0.11	MDAMB415	N	0	0	0	N
MAP3K1	GLRWRIKKL	BREAST	161	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	Y	11	12	0	N
MAP3K1	IKKLSKGCT	BREAST	166	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	N	1	0	1	N
MAP3K1	KGCTRWMIV	BREAST	171	p.R162fs	c.485_485delG	Frame_Shift_Del	6	0.11	MDAMB415	N	7	0	0	N
MAP3K1	KKLSKGCTR	BREAST	167	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	N	1	0	0	Y
MAP3K1	KLSKGCTRW	BREAST	168	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	Y	5	11	0	N
MAP3K1	LRWRIKKLS	BREAST	162	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	N	2	0	30	N
MAP3K1	LSKGCTRWM	BREAST	169	p.R162fs	c.485_485delG	Frame_Shift_Del	6	0.11	MDAMB415	N	3	0	1	N
MAP3K1	PAAAPAGLR	BREAST	155	p.R162fs	c.485_485delG	Frame_Shift_Del	2	0.11	MDAMB415	N	0	0	0	N
MAP3K1	PAGLRWRIK	BREAST	159	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	N	0	0	0	N
MAP3K1	RIKKLSKGC	BREAST	165	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	N	1	0	0	N
MAP3K1	RWMIVQRNE	BREAST	175	p.R162fs	c.485_485delG	Frame_Shift_Del	6	0.11	MDAMB415	N	0	0	0	N
MAP3K1	RWRIKKLSK	BREAST	163	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	N	1	0	0	N
MAP3K1	SKGCTRWMI	BREAST	170	p.R162fs	c.485_485delG	Frame_Shift_Del	6	0.11	MDAMB415	Y	2	13	0	N
MAP3K1	SPAAAPAGL	BREAST	154	p.R162fs	c.485_485delG	Frame_Shift_Del	1	0.11	MDAMB415	N	15	0	0	N
MAP3K1	TRWMIVQRN	BREAST	174	p.R162fs	c.485_485delG	Frame_Shift_Del	6	0.11	MDAMB415	N	2	0	0	N
MAP3K1	WRIKKLSKG	BREAST	164	p.R162fs	c.485_485delG	Frame_Shift_Del	5	0.11	MDAMB415	N	3	0	24	N
MAP3K1	KQGDPSKIA	ENDOMETRIUM	1072	p.S1077fs	c.3231_3231delA	Frame_Shift_Del	2	0.22	HEC1A	N	5	0	0	N
MAP3K1	KQGDPSKIA	ENDOMETRIUM	1072	p.S1077fs	c.3231_3231delA	Frame_Shift_Del	2	0.22	HEC1B	N	5	0	0	N
MAP3K1	SKQGDPSKI	ENDOMETRIUM	1071	p.S1077fs	c.3231_3231delA	Frame_Shift_Del	1	0.22	HEC1A	N	1	0	0	N
MAP3K1	SKQGDPSKI	ENDOMETRIUM	1071	p.S1077fs	c.3231_3231delA	Frame_Shift_Del	1	0.22	HEC1B	N	1	0	0	N
MAP3K1	ACGTFCIHL	LARGE_INTESTINE	350	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	Y	6	9	0	N
MAP3K1	ADESPGEVQ	ENDOMETRIUM	229	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	Y
MAP3K1	ADTATDVSK	ENDOMETRIUM	995	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	ADTILVKCA	LARGE_INTESTINE	684	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	4	0	0	N
MAP3K1	AEAIQLVVE	BREAST	866	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	2	0	0	N
MAP3K1	AEEEEAVAI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1183	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	6	0	0	N
MAP3K1	AEKHSYHLA	ENDOMETRIUM	1451	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	7	0	0	N
MAP3K1	AIQLVVEDT	BREAST	868	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	0	0	0	N
MAP3K1	APSHNTIQK	SOFT_TISSUE	402	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	Y	1	12	0	N
MAP3K1	APSIHSHLS	LARGE_INTESTINE	1470	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	N	3	0	0	N
MAP3K1	APSRNPIQK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	402	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	Y	1	15	0	Y
MAP3K1	ASKGRCSPS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	244	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	1	0	0	N
MAP3K1	ASPASKGRC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	241	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	1	0	0	N
MAP3K1	ATTAPSIHS	LARGE_INTESTINE	1467	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
MAP3K1	AVAIAMAMS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1188	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	0	0	0	N
MAP3K1	AVFGAAARL	LUNG	1387	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	N	16	0	0	N
MAP3K1	AWKHGWLER	ENDOMETRIUM	196	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	Y	2	11	0	N
MAP3K1	CACGTFCIH	LARGE_INTESTINE	349	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	N	0	0	0	N
MAP3K1	CDDSFDCSS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1091	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	1	0	0	Y
MAP3K1	CGTFCIHLL	LARGE_INTESTINE	351	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	N	10	0	0	N
MAP3K1	CMPAWKHGW	ENDOMETRIUM	193	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	N	2	0	0	N
MAP3K1	CPLCRSMWR	LARGE_INTESTINE	488	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	4	0	0	N
MAP3K1	CRSKWRPHD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	491	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	1	0	0	N
MAP3K1	CRSMWRSHD	LARGE_INTESTINE	491	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	1	0	0	N
MAP3K1	CSCACGTFC	LARGE_INTESTINE	347	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	N	1	0	0	N
MAP3K1	CSPSPGNSP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	249	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	0	0	0	N
MAP3K1	CYVWSVGCA	STOMACH	1430	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	N	3	0	0	N
MAP3K1	DCSSNSSNA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1096	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	1	0	0	N
MAP3K1	DDSFDCSSN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1092	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	1	0	0	N
MAP3K1	DDTYKDYVN	CENTRAL_NERVOUS_SYSTEM	1164	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	1	0	0	N
MAP3K1	DESPGEVQA	ENDOMETRIUM	230	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	Y	5	9	0	Y
MAP3K1	DIITIQQDT	ENDOMETRIUM	1215	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	1	0	0	N
MAP3K1	DMVEACCSV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	630	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	Y	4	9	0	N
MAP3K1	DPMLWIKTL	ENDOMETRIUM	372	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	Y	21	9	0	N
MAP3K1	DSFDCSSNS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1093	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	1	0	0	N
MAP3K1	DTATDVSKH	ENDOMETRIUM	996	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
MAP3K1	DTIIIQQDT	LUNG	1215	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	3	0	0	N
MAP3K1	DTYKDYVNH	CENTRAL_NERVOUS_SYSTEM	1165	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	0	0	0	N
MAP3K1	DVSKHRLHG	OVARY	1000	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	N	0	0	0	N
MAP3K1	DYVNHNQKC	CENTRAL_NERVOUS_SYSTEM	1169	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	4	0	0	N
MAP3K1	EAEEEEAVA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1182	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	3	0	0	N
MAP3K1	EAIQLVVED	BREAST	867	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	0	0	0	N
MAP3K1	EAVAIAMAM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1187	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	8	0	0	N
MAP3K1	EDIITIQQD	ENDOMETRIUM	1214	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	0	0	0	N
MAP3K1	EDTIIIQQD	LUNG	1214	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	0	0	0	N
MAP3K1	EEAVAIAMA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1186	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	6	0	0	N
MAP3K1	EEEAVAIAM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1185	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	6	0	0	N
MAP3K1	EEEEAVAIA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1184	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	5	0	0	N
MAP3K1	EIAEAIQLV	BREAST	864	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	Y	4	11	0	N
MAP3K1	EISSPECTV	LUNG	898	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	2	0	0	Y
MAP3K1	EKHSYHLAL	ENDOMETRIUM	1452	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	6	0	0	N
MAP3K1	EMENKETLQ	OVARY	163	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	1	0	0	Y
MAP3K1	EMNHLADES	ENDOMETRIUM	224	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
MAP3K1	ENDDTYKDY	CENTRAL_NERVOUS_SYSTEM	1162	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	3	0	0	N
MAP3K1	ENGEDIITI	ENDOMETRIUM	1211	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	Y	2	12	0	N
MAP3K1	ENGEDTIII	LUNG	1211	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	3	0	0	N
MAP3K1	ENKETLQGL	OVARY	165	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	Y	6	18	0	N
MAP3K1	ENQLIHRDV	LARGE_INTESTINE	1362	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	N
MAP3K1	EPSDPMLWI	ENDOMETRIUM	369	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	13	0	0	N
MAP3K1	ERRNKRGPV	LARGE_INTESTINE	203	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	5	0	0	Y
MAP3K1	ETLQGLHKM	OVARY	168	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	4	0	0	N
MAP3K1	ETTEISSPE	LUNG	895	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	0	0	0	N
MAP3K1	EWLERRNKR	LARGE_INTESTINE	200	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	1	0	0	Y
MAP3K1	FDCSSNSSN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1095	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	4	0	0	N
MAP3K1	FVMLWVFQL	LARGE_INTESTINE	360	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	N	17	0	47	N
MAP3K1	GDMVEACCS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	629	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	N	3	0	0	N
MAP3K1	GEDIITIQQ	ENDOMETRIUM	1213	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	0	0	0	N
MAP3K1	GEDTIIIQQ	LUNG	1213	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	0	0	0	N
MAP3K1	GPQNCSCAC	LARGE_INTESTINE	343	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	N	4	0	0	N
MAP3K1	GQQYGRSCY	STOMACH	1423	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	N	6	0	0	N
MAP3K1	GQRLRIAVF	LUNG	1381	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	Y	8	10	0	N
MAP3K1	GRCSPSPGN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	247	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	2	0	0	N
MAP3K1	GRITPPRRV	ENDOMETRIUM	282	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	Y	5	11	0	N
MAP3K1	GRSCYVWSV	STOMACH	1427	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	Y	6	11	0	N
MAP3K1	GSEMNHLAD	ENDOMETRIUM	222	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
MAP3K1	GTQQIPPVY	ENDOMETRIUM	545	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	N	7	0	0	N
MAP3K1	GWLERRNRR	ENDOMETRIUM	200	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	Y	2	9	0	N
MAP3K1	HENQLIHRD	LARGE_INTESTINE	1361	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	N
MAP3K1	HEWLERRNK	LARGE_INTESTINE	199	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	1	0	0	Y
MAP3K1	HGFIPCRIP	OVARY	1007	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	N	0	0	0	N
MAP3K1	HGWLERRNR	ENDOMETRIUM	199	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	N	1	0	0	N
MAP3K1	HLADESPGE	ENDOMETRIUM	227	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	Y
MAP3K1	HLLFVMLWV	LARGE_INTESTINE	357	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	Y	8	11	0	N
MAP3K1	HNTIQKFVS	SOFT_TISSUE	405	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	0	0	0	N
MAP3K1	HRLHGFIPC	OVARY	1004	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	N	5	0	0	N
MAP3K1	HSHLSPGLR	LARGE_INTESTINE	1474	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	N	3	0	0	N
MAP3K1	HSYHLALIF	ENDOMETRIUM	1454	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	11	0	0	N
MAP3K1	IAEAIQLVV	BREAST	865	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	8	0	0	N
MAP3K1	IAVFGAAAR	LUNG	1386	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	Y	4	9	0	N
MAP3K1	ICPLCRSMW	LARGE_INTESTINE	487	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	2	0	0	N
MAP3K1	IHLLFVMLW	LARGE_INTESTINE	356	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	Y	5	11	36	N
MAP3K1	IHSHLSPGL	LARGE_INTESTINE	1473	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	N	5	0	2	N
MAP3K1	IITIQQDTP	ENDOMETRIUM	1216	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	0	0	0	N
MAP3K1	IKAPSHNTI	SOFT_TISSUE	400	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	2	0	0	N
MAP3K1	IKAPSRNPI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	400	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	N	3	0	1	N
MAP3K1	IKTLKNFEV	ENDOMETRIUM	377	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	4	0	8	N
MAP3K1	IPPVYKDLA	ENDOMETRIUM	549	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	N	8	0	0	N
MAP3K1	IQLVVEDTL	BREAST	869	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	19	0	0	N
MAP3K1	ISGDMVEAC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	627	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	Y	1	10	7	N
MAP3K1	ISSPECTVH	LUNG	899	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	0	0	0	Y
MAP3K1	ITIQQDTPE	ENDOMETRIUM	1217	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	0	0	0	N
MAP3K1	ITPPRRVPS	ENDOMETRIUM	284	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	3	0	0	N
MAP3K1	KAPSHNTIQ	SOFT_TISSUE	401	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	0	0	0	N
MAP3K1	KAPSRNPIQ	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	401	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	N	0	0	0	N
MAP3K1	KCDDSFDCS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1090	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	0	0	0	N
MAP3K1	KDYVNHNQK	CENTRAL_NERVOUS_SYSTEM	1168	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	0	0	0	N
MAP3K1	KETLQGLHK	OVARY	167	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	2	0	0	N
MAP3K1	KGRCSPSPG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	246	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	1	0	0	N
MAP3K1	KHGWLERRN	ENDOMETRIUM	198	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	N	1	0	0	N
MAP3K1	KHRLHGFIP	OVARY	1003	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	N	1	0	0	N
MAP3K1	KHSYHLALI	ENDOMETRIUM	1453	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	5	0	0	N
MAP3K1	KRGPVVVKP	LARGE_INTESTINE	207	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	2	0	0	N
MAP3K1	KWRPHDFYS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	494	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	0	0	0	N
MAP3K1	LADESPGEV	ENDOMETRIUM	228	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	5	0	0	Y
MAP3K1	LCRSKWRPH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	490	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	2	0	0	N
MAP3K1	LCRSMWRSH	LARGE_INTESTINE	490	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	0	0	0	N
MAP3K1	LERRNKRGP	LARGE_INTESTINE	202	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	0	0	13	N
MAP3K1	LETTEISSP	LUNG	894	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	1	0	0	N
MAP3K1	LFVMLWVFQ	LARGE_INTESTINE	359	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	N	0	0	5	N
MAP3K1	LHENQLIHR	LARGE_INTESTINE	1360	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	2	0	0	N
MAP3K1	LHGFIPCRI	OVARY	1006	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	N	5	0	13	N
MAP3K1	LICPLCRSM	LARGE_INTESTINE	486	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	2	0	0	N
MAP3K1	LIHRDVKGA	LARGE_INTESTINE	1365	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	2	0	16	N
MAP3K1	LLFVMLWVF	LARGE_INTESTINE	358	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	N	13	0	4	N
MAP3K1	LLQPVADTI	LARGE_INTESTINE	679	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	10	0	0	N
MAP3K1	LQGLHKMDD	OVARY	170	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	0	0	14	Y
MAP3K1	LQPVADTIL	LARGE_INTESTINE	680	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	10	0	0	N
MAP3K1	LQRLLQPVA	LARGE_INTESTINE	676	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	5	0	6	N
MAP3K1	LQVENGEDT	LUNG	1208	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	5	0	0	N
MAP3K1	LRIAVFGAA	LUNG	1384	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	N	5	0	5	N
MAP3K1	LSYLHENQL	LARGE_INTESTINE	1357	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	13	0	0	Y
MAP3K1	LVVEDTLDG	BREAST	871	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	0	0	29	N
MAP3K1	LWIKTLKNF	ENDOMETRIUM	375	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	3	0	9	N
MAP3K1	LWVFQLEPS	LARGE_INTESTINE	363	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	N	0	0	0	N
MAP3K1	MEAEEEEAV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1181	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	8	0	0	N
MAP3K1	MENKETLQG	OVARY	164	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	0	0	11	N
MAP3K1	MLWIKTLKN	ENDOMETRIUM	374	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	0	0	18	N
MAP3K1	MLWVFQLEP	LARGE_INTESTINE	362	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	N	3	0	0	N
MAP3K1	MNHLADESP	ENDOMETRIUM	225	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	MPAWKHGWL	ENDOMETRIUM	194	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	N	16	0	0	N
MAP3K1	MVEACCSVL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	631	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	N	7	0	2	N
MAP3K1	MWRSHDFYS	LARGE_INTESTINE	494	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	0	0	0	N
MAP3K1	NAEKHSYHL	ENDOMETRIUM	1450	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	8	0	0	N
MAP3K1	NCSCACGTF	LARGE_INTESTINE	346	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	N	4	0	0	N
MAP3K1	NDDTYKDYV	CENTRAL_NERVOUS_SYSTEM	1163	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	4	0	0	N
MAP3K1	NGEDIITIQ	ENDOMETRIUM	1212	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	0	0	0	N
MAP3K1	NGEDTIIIQ	LUNG	1212	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	1	0	0	N
MAP3K1	NHLADESPG	ENDOMETRIUM	226	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	NKETLQGLH	OVARY	166	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	1	0	0	N
MAP3K1	NKRGPVVVK	LARGE_INTESTINE	206	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	1	0	0	N
MAP3K1	NNYLETTEI	LUNG	891	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	7	0	0	N
MAP3K1	NPIQKFVSR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	406	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	N	4	0	0	N
MAP3K1	NQLIHRDVK	LARGE_INTESTINE	1363	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	5	0	0	N
MAP3K1	NYLETTEIS	LUNG	892	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	2	0	0	N
MAP3K1	PADTATDVS	ENDOMETRIUM	994	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	PASKGRCSP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	243	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	0	0	0	N
MAP3K1	PAWKHGWLE	ENDOMETRIUM	195	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	N	0	0	0	N
MAP3K1	PHDFYSHEL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	497	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	2	0	0	N
MAP3K1	PIQKFVSRM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	407	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	N	1	0	0	N
MAP3K1	PLCRSKWRP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	489	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	0	0	0	N
MAP3K1	PLCRSMWRS	LARGE_INTESTINE	489	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	0	0	0	N
MAP3K1	PMLWIKTLK	ENDOMETRIUM	373	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	1	0	0	N
MAP3K1	PPRRVPSPD	ENDOMETRIUM	286	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
MAP3K1	PPVYKDLAE	ENDOMETRIUM	550	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
MAP3K1	PQNCSCACG	LARGE_INTESTINE	344	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	N	0	0	0	N
MAP3K1	PRRVPSPDG	ENDOMETRIUM	287	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	PSDPMLWIK	ENDOMETRIUM	370	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	1	0	0	N
MAP3K1	PSHNTIQKF	SOFT_TISSUE	403	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	1	0	0	N
MAP3K1	PSIHSHLSP	LARGE_INTESTINE	1471	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
MAP3K1	PSRNPIQKF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	403	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	N	1	0	0	N
MAP3K1	PSVPADTAT	ENDOMETRIUM	991	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	PVADTILVK	LARGE_INTESTINE	682	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	3	0	0	N
MAP3K1	PVYKDLAEP	ENDOMETRIUM	551	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
MAP3K1	PWNAEKHSY	ENDOMETRIUM	1448	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	0	0	0	N
MAP3K1	QGLHKMDDR	OVARY	171	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	1	0	0	Y
MAP3K1	QIPPVYKDL	ENDOMETRIUM	548	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	Y	11	9	0	N
MAP3K1	QLIHRDVKG	LARGE_INTESTINE	1364	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	0	0	0	N
MAP3K1	QLVVEDTLD	BREAST	870	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	0	0	0	N
MAP3K1	QNCSCACGT	LARGE_INTESTINE	345	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	N	0	0	0	N
MAP3K1	QPVADTILV	LARGE_INTESTINE	681	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	12	0	0	N
MAP3K1	QQIPPVYKD	ENDOMETRIUM	547	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
MAP3K1	QQYGRSCYV	STOMACH	1424	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	Y	11	11	0	N
MAP3K1	QRLLQPVAD	LARGE_INTESTINE	677	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	1	0	0	N
MAP3K1	QRLRIAVFG	LUNG	1382	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	N	1	0	0	N
MAP3K1	QTSISGDMV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	624	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	N	1	0	0	N
MAP3K1	QVENGEDTI	LUNG	1209	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	3	0	0	N
MAP3K1	QYGRSCYVW	STOMACH	1425	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	N	2	0	0	N
MAP3K1	RCSPSPGNS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	248	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	0	0	0	N
MAP3K1	RIAVFGAAA	LUNG	1385	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	N	2	0	0	N
MAP3K1	RIKAPSHNT	SOFT_TISSUE	399	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	0	0	0	N
MAP3K1	RIKAPSRNP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	399	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	N	0	0	0	N
MAP3K1	RITPPRRVP	ENDOMETRIUM	283	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	RLHGFIPCR	OVARY	1005	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	Y	8	9	0	N
MAP3K1	RLLQPVADT	LARGE_INTESTINE	678	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	5	0	0	N
MAP3K1	RLRIAVFGA	LUNG	1383	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	Y	5	11	0	N
MAP3K1	RNKRGPVVV	LARGE_INTESTINE	205	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	4	0	0	N
MAP3K1	RNPIQKFVS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	405	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	N	0	0	0	N
MAP3K1	RPHDFYSHE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	496	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	1	0	0	N
MAP3K1	RRNKRGPVV	LARGE_INTESTINE	204	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	Y	4	11	0	Y
MAP3K1	RRVPSPDGF	ENDOMETRIUM	288	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	5	0	0	N
MAP3K1	RSCYVWSVG	STOMACH	1428	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	N	1	0	0	N
MAP3K1	RSKWRPHDF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	492	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	Y	6	9	0	N
MAP3K1	RSMWRSHDF	LARGE_INTESTINE	492	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	Y	6	11	0	N
MAP3K1	RVPSPDGFS	ENDOMETRIUM	289	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	SATTAPSIH	LARGE_INTESTINE	1466	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
MAP3K1	SCACGTFCI	LARGE_INTESTINE	348	p.R351C	c.1051C>T	Missense_Mutation	1	0.11	HCT116	Y	2	9	0	N
MAP3K1	SCYVWSVGC	STOMACH	1429	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	N	0	0	0	N
MAP3K1	SDPMLWIKT	ENDOMETRIUM	371	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	3	0	0	N
MAP3K1	SEMNHLADE	ENDOMETRIUM	223	p.A230D	c.689C>A	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
MAP3K1	SFDCSSNSS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1094	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	0	0	0	N
MAP3K1	SGDMVEACC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	628	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	N	1	0	0	N
MAP3K1	SHNTIQKFV	SOFT_TISSUE	404	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	3	0	0	N
MAP3K1	SIHSHLSPG	LARGE_INTESTINE	1472	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
MAP3K1	SISGDMVEA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	626	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	N	0	0	0	N
MAP3K1	SKCDDSFDC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1089	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	1	0	0	N
MAP3K1	SKGRCSPSP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	245	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	0	0	0	N
MAP3K1	SKHRLHGFI	OVARY	1002	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	N	3	0	0	N
MAP3K1	SKWRPHDFY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	493	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	3	0	0	N
MAP3K1	SMWRSHDFY	LARGE_INTESTINE	493	p.K494M	c.1481A>T	Missense_Mutation	1	0.11	HT55	N	7	0	0	N
MAP3K1	SPASKGRCS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	242	p.R249C	c.745C>T	Missense_Mutation	1	0.11	KYO1	N	3	0	0	N
MAP3K1	SQTSISGDM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	623	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	N	6	0	0	N
MAP3K1	SRIKAPSHN	SOFT_TISSUE	398	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	2	0	0	N
MAP3K1	SRNPIQKFV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	404	p.T407P	c.1219A>C	Missense_Mutation	1	0.11	HT	Y	4	9	0	N
MAP3K1	SSKCDDSFD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1088	p.G1096D	c.3287G>A	Missense_Mutation	1	0.11	HPBALL	N	0	0	0	Y
MAP3K1	SSRIKAPSH	SOFT_TISSUE	397	p.R405H	c.1214G>A	Missense_Mutation	1	0.11	SKUT1	N	0	0	0	N
MAP3K1	SSTPSVPAD	ENDOMETRIUM	988	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	STPSVPADT	ENDOMETRIUM	989	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	2	0	0	Y
MAP3K1	SVPADTATD	ENDOMETRIUM	992	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	SYHLALIFK	ENDOMETRIUM	1455	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	Y	2	11	0	N
MAP3K1	SYLHENQLI	LARGE_INTESTINE	1358	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	Y	7	11	0	Y
MAP3K1	TAPSIHSHL	LARGE_INTESTINE	1469	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	Y	15	10	0	N
MAP3K1	TCMPAWKHG	ENDOMETRIUM	192	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	N	0	0	0	N
MAP3K1	TDVSKHRLH	OVARY	999	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	N	1	0	0	N
MAP3K1	TEISSPECT	LUNG	897	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	5	0	0	N
MAP3K1	TGQRLRIAV	LUNG	1380	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	N	5	0	0	N
MAP3K1	TIIIQQDTP	LUNG	1216	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	0	0	0	N
MAP3K1	TIQQDTPET	ENDOMETRIUM	1218	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	0	0	0	N
MAP3K1	TLQGLHKMD	OVARY	169	p.K171Q	c.511A>C	Missense_Mutation	1	0.11	MCAS	N	0	0	0	N
MAP3K1	TPPRRVPSP	ENDOMETRIUM	285	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
MAP3K1	TPSVPADTA	ENDOMETRIUM	990	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	N	8	0	0	N
MAP3K1	TQQIPPVYK	ENDOMETRIUM	546	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	Y	3	15	0	N
MAP3K1	TSISGDMVE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	625	p.V631M	c.1891G>A	Missense_Mutation	1	0.11	SUDHL8	N	0	0	0	N
MAP3K1	TTAPSIHSH	LARGE_INTESTINE	1468	p.P1474H	c.4421C>A	Missense_Mutation	1	0.11	HCT15	Y	0	13	0	N
MAP3K1	TTEISSPEC	LUNG	896	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	2	0	0	N
MAP3K1	TYKDYVNHN	CENTRAL_NERVOUS_SYSTEM	1166	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	2	0	0	N
MAP3K1	VADTILVKC	LARGE_INTESTINE	683	p.V684A	c.2051T>C	Missense_Mutation	1	0.11	SNU1040	N	3	0	0	N
MAP3K1	VAIAMAMSA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1189	p.L1189V	c.3565T>G	Missense_Mutation	1	0.11	L540	N	8	0	16	N
MAP3K1	VENGEDIIT	ENDOMETRIUM	1210	p.I1218T	c.3653T>C	Missense_Mutation	1	0.11	MFE319	N	5	0	0	N
MAP3K1	VENGEDTII	LUNG	1210	p.I1216T	c.3647T>C	Missense_Mutation	1	0.11	RERFLCSQ1	N	8	0	0	N
MAP3K1	VFGAAARLA	LUNG	1388	p.D1388V	c.4163A>T	Missense_Mutation	1	0.11	NCIH1648	N	2	0	5	N
MAP3K1	VMLWVFQLE	LARGE_INTESTINE	361	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	N	0	0	1	N
MAP3K1	VPADTATDV	ENDOMETRIUM	993	p.G996D	c.2987G>A	Missense_Mutation	1	0.11	HEC108	Y	13	12	0	N
MAP3K1	VPSPDGFSP	ENDOMETRIUM	290	p.A290V	c.869C>T	Missense_Mutation	1	0.11	HEC108	N	2	0	0	N
MAP3K1	VSKHRLHGF	OVARY	1001	p.Q1007H	c.3021G>T	Missense_Mutation	1	0.11	OC316	Y	8	9	3	N
MAP3K1	VVEDTLDGQ	BREAST	872	p.G872V	c.2615G>T	Missense_Mutation	1	0.11	CAMA1	N	1	0	6	N
MAP3K1	VYKDLAEPW	ENDOMETRIUM	552	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	4	N
MAP3K1	WIKTLKNFE	ENDOMETRIUM	376	p.R377I	c.1130G>T	Missense_Mutation	1	0.11	JHUEM7	N	2	0	0	N
MAP3K1	WKHGWLERR	ENDOMETRIUM	197	p.E200G	c.599A>G	Missense_Mutation	1	0.11	AN3CA	N	3	0	0	Y
MAP3K1	WLERRNKRG	LARGE_INTESTINE	201	p.R207K	c.620G>A	Missense_Mutation	1	0.11	GP2D	N	1	0	0	N
MAP3K1	WNAEKHSYH	ENDOMETRIUM	1449	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	2	0	0	N
MAP3K1	WRPHDFYSH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	495	p.S497P	c.1489T>C	Missense_Mutation	1	0.11	NALM19	N	4	0	4	N
MAP3K1	WVFQLEPSD	LARGE_INTESTINE	364	p.R364W	c.1090C>T	Missense_Mutation	1	0.11	SNUC2A	N	2	0	0	N
MAP3K1	YGRSCYVWS	STOMACH	1426	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	N	3	0	0	N
MAP3K1	YGTQQIPPV	ENDOMETRIUM	544	p.A552V	c.1655C>T	Missense_Mutation	1	0.11	HEC6	N	11	0	0	N
MAP3K1	YHLALIFKI	ENDOMETRIUM	1456	p.N1456Y	c.4366A>T	Missense_Mutation	1	0.11	HEC151	N	9	0	25	N
MAP3K1	YKDYVNHNQ	CENTRAL_NERVOUS_SYSTEM	1167	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	N	2	0	2	N
MAP3K1	YLETTEISS	LUNG	893	p.N899I	c.2696A>T	Missense_Mutation	1	0.11	NCIH1944	N	4	0	0	N
MAP3K1	YLHENQLIH	LARGE_INTESTINE	1359	p.I1365L	c.4093A>C	Missense_Mutation	1	0.11	CCK81	N	3	0	2	Y
MAP3K1	YVNHNQKCK	CENTRAL_NERVOUS_SYSTEM	1170	p.D1170Y	c.3508G>T	Missense_Mutation	1	0.11	T98G	Y	4	13	16	Y
MAP3K1	YVWSVGCAI	STOMACH	1431	p.D1431Y	c.4291G>T	Missense_Mutation	1	0.11	NUGC3	Y	15	11	8	N
MAP3K1	ASKGRHSPS	ENDOMETRIUM	244	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	2	0	0	N
MAP3K1	ASKGRHSPS	PANCREAS	244	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	2	0	0	N
MAP3K1	ASPASKGRH	ENDOMETRIUM	241	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	0	0	0	N
MAP3K1	ASPASKGRH	PANCREAS	241	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	0	0	0	N
MAP3K1	DPVLWRKTL	OESOPHAGUS	372	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	19	0	0	N
MAP3K1	DPVLWRKTL	ENDOMETRIUM	372	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	19	0	0	N
MAP3K1	EPSDPVLWR	OESOPHAGUS	369	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	Y	4	10	0	N
MAP3K1	EPSDPVLWR	ENDOMETRIUM	369	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	Y	4	10	0	N
MAP3K1	FQLEPSDPV	OESOPHAGUS	366	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	13	0	3	N
MAP3K1	FQLEPSDPV	ENDOMETRIUM	366	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	13	0	3	N
MAP3K1	GRHSPSPGN	ENDOMETRIUM	247	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	2	0	0	N
MAP3K1	GRHSPSPGN	PANCREAS	247	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	2	0	0	N
MAP3K1	HSPSPGNSP	ENDOMETRIUM	249	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	0	0	0	N
MAP3K1	HSPSPGNSP	PANCREAS	249	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	0	0	0	N
MAP3K1	KGRHSPSPG	ENDOMETRIUM	246	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	1	0	0	N
MAP3K1	KGRHSPSPG	PANCREAS	246	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	1	0	0	N
MAP3K1	LEPSDPVLW	OESOPHAGUS	368	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	7	0	0	N
MAP3K1	LEPSDPVLW	ENDOMETRIUM	368	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	7	0	0	N
MAP3K1	PASKGRHSP	ENDOMETRIUM	243	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	0	0	0	N
MAP3K1	PASKGRHSP	PANCREAS	243	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	0	0	0	N
MAP3K1	PSDPVLWRK	OESOPHAGUS	370	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	1	0	0	N
MAP3K1	PSDPVLWRK	ENDOMETRIUM	370	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	1	0	0	N
MAP3K1	PVLWRKTLK	OESOPHAGUS	373	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	2	0	0	N
MAP3K1	PVLWRKTLK	ENDOMETRIUM	373	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	2	0	0	N
MAP3K1	QLEPSDPVL	OESOPHAGUS	367	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	8	0	0	N
MAP3K1	QLEPSDPVL	ENDOMETRIUM	367	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	8	0	0	N
MAP3K1	RHSPSPGNS	ENDOMETRIUM	248	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	1	0	0	N
MAP3K1	RHSPSPGNS	PANCREAS	248	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	1	0	0	N
MAP3K1	SDPVLWRKT	OESOPHAGUS	371	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	3	0	0	N
MAP3K1	SDPVLWRKT	ENDOMETRIUM	371	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	3	0	0	N
MAP3K1	SKGRHSPSP	ENDOMETRIUM	245	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	0	0	0	N
MAP3K1	SKGRHSPSP	PANCREAS	245	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	0	0	0	N
MAP3K1	SPASKGRHS	ENDOMETRIUM	242	p.R249H	c.746G>A	Missense_Mutation	1	0.22	MFE296	N	3	0	0	N
MAP3K1	SPASKGRHS	PANCREAS	242	p.R249H	c.746G>A	Missense_Mutation	1	0.22	PK45H	N	3	0	0	N
MAP3K1	VLWRKTLKN	OESOPHAGUS	374	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	ECGI10	N	0	0	9	N
MAP3K1	VLWRKTLKN	ENDOMETRIUM	374	p.M374V	c.1120A>G	Missense_Mutation	1	0.22	JHUEM1	N	0	0	9	N
MAP3K1	CRRLMAIAD	ENDOMETRIUM	853	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	N	1	0	0	N
MAP3K1	CRRLMAIAD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	853	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	N	1	0	0	N
MAP3K1	CRRLMAIAD	LARGE_INTESTINE	853	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	N	1	0	0	N
MAP3K1	FTRMCRRLM	ENDOMETRIUM	849	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	N	7	0	21	N
MAP3K1	FTRMCRRLM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	849	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	N	7	0	21	N
MAP3K1	FTRMCRRLM	LARGE_INTESTINE	849	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	N	7	0	21	N
MAP3K1	HFTRMCRRL	ENDOMETRIUM	848	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	Y	7	10	0	N
MAP3K1	HFTRMCRRL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	848	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	Y	7	10	0	N
MAP3K1	HFTRMCRRL	LARGE_INTESTINE	848	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	Y	7	10	0	N
MAP3K1	MCRRLMAIA	ENDOMETRIUM	852	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	N	3	0	2	N
MAP3K1	MCRRLMAIA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	852	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	N	3	0	2	N
MAP3K1	MCRRLMAIA	LARGE_INTESTINE	852	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	N	3	0	2	N
MAP3K1	RMCRRLMAI	ENDOMETRIUM	851	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	Y	12	11	0	N
MAP3K1	RMCRRLMAI	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	851	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	Y	12	11	0	N
MAP3K1	RMCRRLMAI	LARGE_INTESTINE	851	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	Y	12	11	0	N
MAP3K1	SSTHFTRMC	ENDOMETRIUM	845	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	N	1	0	0	N
MAP3K1	SSTHFTRMC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	845	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	N	1	0	0	N
MAP3K1	SSTHFTRMC	LARGE_INTESTINE	845	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	N	1	0	0	N
MAP3K1	STHFTRMCR	ENDOMETRIUM	846	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	Y	6	9	0	N
MAP3K1	STHFTRMCR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	846	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	Y	6	9	0	N
MAP3K1	STHFTRMCR	LARGE_INTESTINE	846	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	Y	6	9	0	N
MAP3K1	THFTRMCRR	ENDOMETRIUM	847	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	Y	1	9	0	N
MAP3K1	THFTRMCRR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	847	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	Y	1	9	0	N
MAP3K1	THFTRMCRR	LARGE_INTESTINE	847	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	Y	1	9	0	N
MAP3K1	TRMCRRLMA	ENDOMETRIUM	850	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	HEC59	N	3	0	0	N
MAP3K1	TRMCRRLMA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	850	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	PF382	N	3	0	0	N
MAP3K1	TRMCRRLMA	LARGE_INTESTINE	850	p.R853C	c.2557C>T	Missense_Mutation	1	0.33	RKO	N	3	0	0	N