Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
FLT3GLLSAGSGRLARGE_INTESTINE982p.S985fsc.2955_2956delTCFrame_Shift_Del50.33GP2DN600N
FLT3GLLSAGSGRLARGE_INTESTINE982p.S985fsc.2955_2956delTCFrame_Shift_Del50.33HCT116N600N
FLT3GLLSAGSGRLARGE_INTESTINE982p.S985fsc.2955_2956delTCFrame_Shift_Del50.33LS411NN600N
FLT3LGLLSAGSGLARGE_INTESTINE981p.S985fsc.2955_2956delTCFrame_Shift_Del40.33GP2DN000N
FLT3LGLLSAGSGLARGE_INTESTINE981p.S985fsc.2955_2956delTCFrame_Shift_Del40.33HCT116N000N
FLT3LGLLSAGSGLARGE_INTESTINE981p.S985fsc.2955_2956delTCFrame_Shift_Del40.33LS411NN000N
FLT3LLSAGSGRRLARGE_INTESTINE983p.S985fsc.2955_2956delTCFrame_Shift_Del60.33GP2DN502N
FLT3LLSAGSGRRLARGE_INTESTINE983p.S985fsc.2955_2956delTCFrame_Shift_Del60.33HCT116N502N
FLT3LLSAGSGRRLARGE_INTESTINE983p.S985fsc.2955_2956delTCFrame_Shift_Del60.33LS411NN502N
FLT3LSAGSGRRFLARGE_INTESTINE984p.S985fsc.2955_2956delTCFrame_Shift_Del60.33GP2DN600N
FLT3LSAGSGRRFLARGE_INTESTINE984p.S985fsc.2955_2956delTCFrame_Shift_Del60.33HCT116N600N
FLT3LSAGSGRRFLARGE_INTESTINE984p.S985fsc.2955_2956delTCFrame_Shift_Del60.33LS411NN600N
FLT3SAGSGRRFVLARGE_INTESTINE985p.S985fsc.2955_2956delTCFrame_Shift_Del50.33GP2DY390N
FLT3SAGSGRRFVLARGE_INTESTINE985p.S985fsc.2955_2956delTCFrame_Shift_Del50.33HCT116Y390N
FLT3SAGSGRRFVLARGE_INTESTINE985p.S985fsc.2955_2956delTCFrame_Shift_Del50.33LS411NY390N