Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
CHD1VREVQRGEKPROSTATE1325p.K1320fsc.3960_3960delAFrame_Shift_Del60.1122RV1N303N
CHD1MIMIKEVLVOVARY225p.K210fsc.629_629delAFrame_Shift_Del60.22IGROV1N502N
CHD1MIMIKEVLVLARGE_INTESTINE225p.K210fsc.629_629delAFrame_Shift_Del60.22LS180N502N
CHD1MMKKIMIMIOVARY220p.K210fsc.629_629delAFrame_Shift_Del60.22IGROV1N1000N
CHD1MMKKIMIMILARGE_INTESTINE220p.K210fsc.629_629delAFrame_Shift_Del60.22LS180N1000N
CHD1MMMKKIMIMOVARY219p.K210fsc.629_629delAFrame_Shift_Del60.22IGROV1N9036N
CHD1MMMKKIMIMLARGE_INTESTINE219p.K210fsc.629_629delAFrame_Shift_Del60.22LS180N9036N
CHD1RMMMKKIMIOVARY218p.K210fsc.629_629delAFrame_Shift_Del60.22IGROV1N1300N
CHD1RMMMKKIMILARGE_INTESTINE218p.K210fsc.629_629delAFrame_Shift_Del60.22LS180N1300N
CHD1RRMMMKKIMOVARY217p.K210fsc.629_629delAFrame_Shift_Del60.22IGROV1N400N
CHD1RRMMMKKIMLARGE_INTESTINE217p.K210fsc.629_629delAFrame_Shift_Del60.22LS180N400N