Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Browse Results ...

The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
ALK	ACGTQRTAP	LUNG	1501	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	N
ALK	APGLQRNPP	LUNG	1508	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	1	0	0	N
ALK	CGTQRTAPG	LUNG	1502	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	N
ALK	ETSPPACGT	LUNG	1496	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	1	0	0	N
ALK	GLQRNPPKR	LUNG	1510	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	6	0	0	N
ALK	GSETSPPAC	LUNG	1494	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	4	0.11	NCIH1836	N	2	0	0	N
ALK	GTQRTAPGL	LUNG	1503	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	6	0	0	Y
ALK	HGSETSPPA	LUNG	1493	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	4	0.11	NCIH1836	N	2	0	0	N
ALK	HKVHGSETS	LUNG	1490	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	3	0.11	NCIH1836	N	1	0	0	N
ALK	KVHGSETSP	LUNG	1491	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	3	0.11	NCIH1836	N	0	0	0	N
ALK	LHKVHGSET	LUNG	1489	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	2	0.11	NCIH1836	N	0	0	0	N
ALK	LQRNPPKRI	LUNG	1511	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	6	0	10	N
ALK	PACGTQRTA	LUNG	1500	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	4	0.11	NCIH1836	N	0	0	0	N
ALK	PGLQRNPPK	LUNG	1509	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	N
ALK	PPACGTQRT	LUNG	1499	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	N
ALK	QRNPPKRII	LUNG	1512	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	Y	3	10	0	N
ALK	QRTAPGLQR	LUNG	1505	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	3	0	0	Y
ALK	RNPPKRIIL	LUNG	1513	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	Y	11	16	0	N
ALK	RTAPGLQRN	LUNG	1506	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	1	0	0	Y
ALK	SETSPPACG	LUNG	1495	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	N
ALK	SPPACGTQR	LUNG	1498	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	3	0	0	N
ALK	TAPGLQRNP	LUNG	1507	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	N
ALK	TQRTAPGLQ	LUNG	1504	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	Y
ALK	TSPPACGTQ	LUNG	1497	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	5	0.11	NCIH1836	N	0	0	0	N
ALK	VHGSETSPP	LUNG	1492	p.S1495fs	c.4485_4485delC	Frame_Shift_Del	4	0.11	NCIH1836	N	0	0	0	N
ALK	AAPVQSQRA	OVARY	165	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	4	0	0	N
ALK	APPSLPDLR	OVARY	213	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	3	0	0	Y
ALK	APVQSQRAV	OVARY	166	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	Y	12	9	0	N
ALK	AREEGVGSG	OVARY	191	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	1	0	0	N
ALK	ATEDPPDAR	OVARY	184	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	5	0	0	N
ALK	AVQLVDSPR	OVARY	173	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	6	0	0	N
ALK	AVRGNSRLP	OVARY	204	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	CGAAPVQSQ	OVARY	163	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	CVGPPRGGG	OVARY	154	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	Y
ALK	DAREEGVGS	OVARY	190	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	3	0	0	N
ALK	DPPDAREEG	OVARY	187	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	DSPRRRATE	OVARY	178	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	EDPPDAREE	OVARY	186	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	EEGVGSGQR	OVARY	193	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	1	0	0	N
ALK	EGCVGPPRG	OVARY	152	p.P158fs	c.474_475insC	Frame_Shift_Ins	2	0.11	OC316	N	0	0	0	N
ALK	EGVGSGQRG	OVARY	194	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	GAAPVQSQR	OVARY	164	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	Y	3	10	0	N
ALK	GCGAAPVQS	OVARY	162	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	GCVGPPRGG	OVARY	153	p.P158fs	c.474_475insC	Frame_Shift_Ins	3	0.11	OC316	N	0	0	0	N
ALK	GGCGAAPVQ	OVARY	161	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	GGGCGAAPV	OVARY	160	p.P158fs	c.474_475insC	Frame_Shift_Ins	3	0.11	OC316	N	7	0	0	N
ALK	GKAVRGNSR	OVARY	202	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	1	0	0	N
ALK	GNSRLPAPP	OVARY	207	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	GPPRGGGCG	OVARY	156	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	GQRGKAVRG	OVARY	199	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	GSGQRGKAV	OVARY	197	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	4	0	0	N
ALK	GVGSGQRGK	OVARY	195	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	3	0	0	N
ALK	KAVRGNSRL	OVARY	203	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	16	0	0	N
ALK	LPAPPSLPD	OVARY	211	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	2	0	0	N
ALK	LVDSPRRRA	OVARY	176	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	Y	2	11	5	N
ALK	NSRLPAPPS	OVARY	208	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	PAPPSLPDL	OVARY	212	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	1	0	0	N
ALK	PDAREEGVG	OVARY	189	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	PPDAREEGV	OVARY	188	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	5	0	0	N
ALK	PPRGGGCGA	OVARY	157	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	4	0	0	N
ALK	PPSLPDLRD	OVARY	214	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	PRGGGCGAA	OVARY	158	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	1	0	0	N
ALK	PRRRATEDP	OVARY	180	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	PSLPDLRDW	OVARY	215	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	1	0	0	N
ALK	PVQSQRAVQ	OVARY	167	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	QLVDSPRRR	OVARY	175	p.P158fs	c.474_475insC	Frame_Shift_Ins	6	0.11	OC316	N	5	0	0	N
ALK	QRAVQLVDS	OVARY	171	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	2	0	0	N
ALK	QRGKAVRGN	OVARY	200	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	2	0	0	N
ALK	QSQRAVQLV	OVARY	169	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	2	0	0	N
ALK	RATEDPPDA	OVARY	183	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	3	0	0	N
ALK	RAVQLVDSP	OVARY	172	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	REEGVGSGQ	OVARY	192	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	RGGGCGAAP	OVARY	159	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	RGKAVRGNS	OVARY	201	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	RGNSRLPAP	OVARY	206	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	0	0	0	N
ALK	RLPAPPSLP	OVARY	210	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	RRATEDPPD	OVARY	182	p.P158fs	c.474_475insC	Frame_Shift_Ins	6	0.11	OC316	N	2	0	0	N
ALK	RRRATEDPP	OVARY	181	p.P158fs	c.474_475insC	Frame_Shift_Ins	6	0.11	OC316	N	3	0	0	N
ALK	SGQRGKAVR	OVARY	198	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	1	0	0	N
ALK	SLPDLRDWS	OVARY	216	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	0	0	0	N
ALK	SPRRRATED	OVARY	179	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	2	0	0	N
ALK	SQRAVQLVD	OVARY	170	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	N	1	0	0	N
ALK	SRLPAPPSL	OVARY	209	p.P158fs	c.474_475insC	Frame_Shift_Ins	4	0.11	OC316	Y	7	10	0	N
ALK	TEDPPDARE	OVARY	185	p.P158fs	c.474_475insC	Frame_Shift_Ins	6	0.11	OC316	N	0	0	0	N
ALK	VDSPRRRAT	OVARY	177	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	1	0	0	N
ALK	VGPPRGGGC	OVARY	155	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	1	0	0	Y
ALK	VGSGQRGKA	OVARY	196	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	2	0	1	N
ALK	VQLVDSPRR	OVARY	174	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	6	0	4	N
ALK	VQSQRAVQL	OVARY	168	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	13	0	2	N
ALK	VRGNSRLPA	OVARY	205	p.P158fs	c.474_475insC	Frame_Shift_Ins	5	0.11	OC316	N	6	0	37	N