Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
AKAP9NMMCQHTMILARGE_INTESTINE46p.K37fsc.109_109delAFrame_Shift_Del60.33SNUC2AN800N
AKAP9NMMCQHTMILARGE_INTESTINE46p.K37fsc.109_109delAFrame_Shift_Del60.33SNUC4N800N
AKAP9NMMCQHTMISTOMACH46p.K37fsc.109_109delAFrame_Shift_Del60.33TGBC11TKBN800N
AKAP9RQAVNMMCQLARGE_INTESTINE42p.K37fsc.109_109delAFrame_Shift_Del60.33SNUC2AN000N
AKAP9RQAVNMMCQLARGE_INTESTINE42p.K37fsc.109_109delAFrame_Shift_Del60.33SNUC4N000N
AKAP9RQAVNMMCQSTOMACH42p.K37fsc.109_109delAFrame_Shift_Del60.33TGBC11TKBN000N