Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
AAK1	AQFQMYRTL	LARGE_INTESTINE	319	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	Y	15	9	0	N
AAK1	FQMYRTLPF	LARGE_INTESTINE	321	p.S311fs	c.933_933delA	Frame_Shift_Del	4	0.11	SW403	N	10	0	43	N
AAK1	FSLSYSRKS	LARGE_INTESTINE	310	p.S311fs	c.933_933delA	Frame_Shift_Del	6	0.11	SW403	N	2	0	8	N
AAK1	IYQVSYFSL	LARGE_INTESTINE	304	p.S311fs	c.933_933delA	Frame_Shift_Del	1	0.11	SW403	Y	11	9	6	N
AAK1	KSAQFQMYR	LARGE_INTESTINE	317	p.S311fs	c.933_933delA	Frame_Shift_Del	6	0.11	SW403	Y	5	9	0	N
AAK1	LPFLQSFLN	LARGE_INTESTINE	327	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	7	0	1	N
AAK1	LSYSRKSAQ	LARGE_INTESTINE	312	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	0	0	6	N
AAK1	MYRTLPFLQ	LARGE_INTESTINE	323	p.S311fs	c.933_933delA	Frame_Shift_Del	4	0.11	SW403	N	0	0	8	Y
AAK1	PFLQSFLNQ	LARGE_INTESTINE	328	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	0	0	0	N
AAK1	QFQMYRTLP	LARGE_INTESTINE	320	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	0	0	0	N
AAK1	QMYRTLPFL	LARGE_INTESTINE	322	p.S311fs	c.933_933delA	Frame_Shift_Del	4	0.11	SW403	Y	17	10	0	N
AAK1	QVSYFSLSY	LARGE_INTESTINE	306	p.S311fs	c.933_933delA	Frame_Shift_Del	3	0.11	SW403	N	5	0	0	N
AAK1	RKSAQFQMY	LARGE_INTESTINE	316	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	3	0	0	N
AAK1	RTLPFLQSF	LARGE_INTESTINE	325	p.S311fs	c.933_933delA	Frame_Shift_Del	4	0.11	SW403	N	13	0	0	N
AAK1	SAQFQMYRT	LARGE_INTESTINE	318	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	3	0	0	N
AAK1	SLSYSRKSA	LARGE_INTESTINE	311	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	2	0	0	N
AAK1	SRKSAQFQM	LARGE_INTESTINE	315	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	Y	3	9	0	N
AAK1	SYFSLSYSR	LARGE_INTESTINE	308	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	3	0	0	N
AAK1	SYSRKSAQF	LARGE_INTESTINE	313	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	Y	4	10	0	N
AAK1	TLPFLQSFL	LARGE_INTESTINE	326	p.S311fs	c.933_933delA	Frame_Shift_Del	4	0.11	SW403	Y	15	9	0	N
AAK1	VSYFSLSYS	LARGE_INTESTINE	307	p.S311fs	c.933_933delA	Frame_Shift_Del	4	0.11	SW403	N	0	0	1	N
AAK1	YFSLSYSRK	LARGE_INTESTINE	309	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	Y	3	13	2	N
AAK1	YQVSYFSLS	LARGE_INTESTINE	305	p.S311fs	c.933_933delA	Frame_Shift_Del	2	0.11	SW403	N	3	0	4	N
AAK1	YRTLPFLQS	LARGE_INTESTINE	324	p.S311fs	c.933_933delA	Frame_Shift_Del	3	0.11	SW403	N	4	0	28	Y
AAK1	YSRKSAQFQ	LARGE_INTESTINE	314	p.S311fs	c.933_933delA	Frame_Shift_Del	5	0.11	SW403	N	2	0	6	N
AAK1	APHSNLCSS	LARGE_INTESTINE	883	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	4	0.11	LS180	N	3	0	0	Y
AAK1	DLLEEFAPH	LARGE_INTESTINE	877	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	1	0.11	LS180	N	0	0	0	N
AAK1	EEFAPHSNL	LARGE_INTESTINE	880	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	4	0.11	LS180	N	10	0	0	N
AAK1	EFAPHSNLC	LARGE_INTESTINE	881	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	5	0.11	LS180	N	1	0	0	N
AAK1	FAPHSNLCS	LARGE_INTESTINE	882	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	4	0.11	LS180	N	4	0	11	N
AAK1	LEEFAPHSN	LARGE_INTESTINE	879	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	3	0.11	LS180	N	3	0	0	N
AAK1	LLEEFAPHS	LARGE_INTESTINE	878	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	2	0.11	LS180	N	2	0	0	N
AAK1	PHSNLCSSP	LARGE_INTESTINE	884	p.P884fs	c.2652_2653insC	Frame_Shift_Ins	5	0.11	LS180	N	0	0	0	N
AAK1	AAQGQKVGS	LARGE_INTESTINE	610	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	1	0	0	N
AAK1	AEELLSKDF	ENDOMETRIUM	708	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	4	0	0	N
AAK1	AGHRCILSD	ENDOMETRIUM	630	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
AAK1	AGHRHILSD	PROSTATE	630	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
AAK1	AKLPETVKA	LUNG	331	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	2	0	0	N
AAK1	AQAQATSQH	ENDOMETRIUM	455	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	N	1	0	0	N
AAK1	AQATSQHQQ	ENDOMETRIUM	457	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
AAK1	AQGQKVGSL	LARGE_INTESTINE	611	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	10	0	0	N
AAK1	ATSQHQQQL	ENDOMETRIUM	459	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	Y	4	9	0	N
AAK1	CILSDVTHS	ENDOMETRIUM	634	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
AAK1	DLGSGSSGG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	15	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	0	0	0	N
AAK1	DSGLRLLSV	LUNG	767	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	5	0	0	N
AAK1	EELLSKDFA	ENDOMETRIUM	709	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	6	0	0	Y
AAK1	ELLSKDFAK	ENDOMETRIUM	710	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	6	0	0	Y
AAK1	EPPVPQGLP	LUNG	837	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	0	0	0	N
AAK1	EQGGSDLGS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	10	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	0	0	0	N
AAK1	ETVKASEAA	LUNG	335	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	3	0	0	N
AAK1	FYHQQQQQQ	ENDOMETRIUM	531	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	2	0	2	Y
AAK1	GGSDLGSGS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	12	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	1	0	0	N
AAK1	GHRCILSDV	ENDOMETRIUM	631	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	3	0	0	N
AAK1	GHRHILSDV	PROSTATE	631	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	3	0	0	N
AAK1	GLEPPVPQG	LUNG	835	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	1	0	0	N
AAK1	GLPSQTESV	LUNG	843	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	Y	6	10	0	N
AAK1	GLRLLSVSD	LUNG	769	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	0	0	0	N
AAK1	GQTVDSGLR	LUNG	763	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	6	0	0	N
AAK1	GSDLGSGSS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	13	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	1	0	0	N
AAK1	HILSDVTHS	PROSTATE	634	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
AAK1	HQQQQQQQQ	ENDOMETRIUM	533	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	0	0	0	Y
AAK1	HRCILSDVT	ENDOMETRIUM	632	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	2	0	0	N
AAK1	HRHILSDVT	PROSTATE	632	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	2	0	0	N
AAK1	IPAKLPETV	LUNG	329	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	13	0	0	N
AAK1	KLPETVKAS	LUNG	332	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	1	0	0	N
AAK1	KLTAEELLS	ENDOMETRIUM	705	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
AAK1	KTQRAGHRC	ENDOMETRIUM	626	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	1	0	0	N
AAK1	KTQRAGHRH	PROSTATE	626	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
AAK1	LEPPVPQGL	LUNG	836	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	11	0	0	N
AAK1	LLSKDFAKL	ENDOMETRIUM	711	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	13	0	0	Y
AAK1	LMQNFYHQQ	ENDOMETRIUM	527	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
AAK1	LPAQAQATS	ENDOMETRIUM	453	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	N	5	0	0	N
AAK1	LPETVKASE	LUNG	333	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	2	0	0	N
AAK1	LRLLSVSDP	LUNG	770	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	1	0	43	N
AAK1	LSKDFAKLG	ENDOMETRIUM	712	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	Y
AAK1	LTAEELLSK	ENDOMETRIUM	706	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	5	0	0	N
AAK1	MQNFYHQQQ	ENDOMETRIUM	528	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	0	0	7	N
AAK1	NFYHQQQQQ	ENDOMETRIUM	530	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	0	0	0	Y
AAK1	PAAQGQKVG	LARGE_INTESTINE	609	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
AAK1	PAKLPETVK	LUNG	330	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	0	0	0	N
AAK1	PAQAQATSQ	ENDOMETRIUM	454	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
AAK1	PETVKASEA	LUNG	334	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	2	0	0	N
AAK1	PIPAKLPET	LUNG	328	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	0	0	0	N
AAK1	PPAAQGQKV	LARGE_INTESTINE	608	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	5	0	0	N
AAK1	PPPAAQGQK	LARGE_INTESTINE	607	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	0	0	0	Y
AAK1	PPVPQGLPS	LUNG	838	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	0	0	0	N
AAK1	PQGLPSQTE	LUNG	841	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	0	0	0	N
AAK1	PVPQGLPSQ	LUNG	839	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	0	0	0	N
AAK1	QAQATSQHQ	ENDOMETRIUM	456	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
AAK1	QATSQHQQQ	ENDOMETRIUM	458	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	N	0	0	0	N
AAK1	QGGSDLGSG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	11	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	0	0	0	N
AAK1	QGLPSQTES	LUNG	842	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	0	0	0	N
AAK1	QLMQNFYHQ	ENDOMETRIUM	526	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
AAK1	QNFYHQQQQ	ENDOMETRIUM	529	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
AAK1	QQLMQNFYH	ENDOMETRIUM	525	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
AAK1	QRAGHRCIL	ENDOMETRIUM	628	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	5	0	0	N
AAK1	QRAGHRHIL	PROSTATE	628	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	5	0	0	N
AAK1	QTTPPPAAQ	LARGE_INTESTINE	604	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
AAK1	QTVDSGLRL	LUNG	764	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	13	0	0	N
AAK1	RAGHRCILS	ENDOMETRIUM	629	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	1	0	0	N
AAK1	RAGHRHILS	PROSTATE	629	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	1	0	0	N
AAK1	RCILSDVTH	ENDOMETRIUM	633	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	N	0	0	0	N
AAK1	REQGGSDLG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	9	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	0	0	0	N
AAK1	RHILSDVTH	PROSTATE	633	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	N	0	0	0	N
AAK1	RLLSVSDPF	LUNG	771	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	10	0	0	N
AAK1	RREQGGSDL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	8	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	Y	5	9	0	N
AAK1	SDLGSGSSG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	14	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	0	0	0	N
AAK1	SGLRLLSVS	LUNG	768	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	1	0	0	N
AAK1	SKDFAKLGE	ENDOMETRIUM	713	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
AAK1	SQHQQQLFL	ENDOMETRIUM	461	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	Y	12	13	0	N
AAK1	SRREQGGSD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	7	p.G15D	c.44G>A	Missense_Mutation	1	0.11	REH	N	1	0	0	N
AAK1	TAEELLSKD	ENDOMETRIUM	707	p.N713S	c.2138A>G	Missense_Mutation	1	0.11	HEC251	N	0	0	0	N
AAK1	TPPPAAQGQ	LARGE_INTESTINE	606	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
AAK1	TQRAGHRCI	ENDOMETRIUM	627	p.R634C	c.1900C>T	Missense_Mutation	1	0.11	HEC6	Y	5	13	0	N
AAK1	TQRAGHRHI	PROSTATE	627	p.R634H	c.1901G>A	Missense_Mutation	1	0.11	22RV1	Y	5	13	0	N
AAK1	TSQHQQQLF	ENDOMETRIUM	460	p.P461S	c.1381C>T	Missense_Mutation	1	0.11	HEC59	N	3	0	0	N
AAK1	TTPPPAAQG	LARGE_INTESTINE	605	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
AAK1	TVDSGLRLL	LUNG	765	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	Y	7	10	0	N
AAK1	TVKASEAAA	LUNG	336	p.P336T	c.1006C>A	Missense_Mutation	1	0.11	NCIH650	N	2	0	0	N
AAK1	VDSGLRLLS	LUNG	766	p.P771R	c.2312C>G	Missense_Mutation	1	0.11	RERFLCAD2	N	2	0	0	N
AAK1	VPQGLPSQT	LUNG	840	p.R843G	c.2527C>G	Missense_Mutation	1	0.11	NCIH1092	N	5	0	0	N
AAK1	VQTTPPPAA	LARGE_INTESTINE	603	p.V611A	c.1832T>C	Missense_Mutation	1	0.11	HRT18	N	4	0	0	N
AAK1	YHQQQQQQQ	ENDOMETRIUM	532	p.Q533H	c.1599G>C	Missense_Mutation	1	0.11	HEC108	N	2	0	0	Y
AAK1	DRGRYVLCD	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	186	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	0	0	0	N
AAK1	DRGRYVLCD	PANCREAS	186	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	0	0	0	N
AAK1	GRYVLCDFG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	188	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	2	0	0	N
AAK1	GRYVLCDFG	PANCREAS	188	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	2	0	0	N
AAK1	HDRGRYVLC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	185	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	2	0	0	N
AAK1	HDRGRYVLC	PANCREAS	185	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	2	0	0	N
AAK1	ILLHDRGRY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	182	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	5	0	13	N
AAK1	ILLHDRGRY	PANCREAS	182	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	5	0	13	N
AAK1	LHDRGRYVL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	184	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	6	0	0	N
AAK1	LHDRGRYVL	PANCREAS	184	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	6	0	0	N
AAK1	LLHDRGRYV	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	183	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	Y	9	12	0	N
AAK1	LLHDRGRYV	PANCREAS	183	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	Y	9	12	0	N
AAK1	NILLHDRGR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	181	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	4	0	0	N
AAK1	NILLHDRGR	PANCREAS	181	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	4	0	0	N
AAK1	RGRYVLCDF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	187	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	8	0	0	N
AAK1	RGRYVLCDF	PANCREAS	187	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	8	0	0	N
AAK1	RYVLCDFGS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	189	p.H189R	c.566A>G	Missense_Mutation	1	0.22	MOLP2	N	2	0	0	N
AAK1	RYVLCDFGS	PANCREAS	189	p.H189R	c.566A>G	Missense_Mutation	1	0.22	PSN1	N	2	0	0	N