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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000224                                                              19     869
NP_000360                                                              19     869
XP_005268094                                                           19     869
XP_005264366                                                           19     869
XP_006712078                                                           19     869
NP_000537                                                              17    4312
NP_001263689                                                           17    4312
NP_001119584                                                           17    4312
NP_001119586                                                           17    4312
NP_001263625                                                           17    4312
NP_001119590                                                           17    4312
NP_001263690                                                           17    4312
NP_001119585                                                           17    4312
NP_001263624                                                           17    4312
NP_001119588                                                           17    4312
NP_001119587                                                           17    4312
NP_001119589                                                           17    4312
NP_001263627                                                           17    4312
NP_001263628                                                           17    4312
NP_001263626                                                           17    4312
NP_001127948                                                           17    4312
NP_056165                                                              17    4312
XP_005270761                                                           17    4312
XP_005270760                                                           17    4312
XP_005270759                                                           17    4312
XP_006710604                                                           17    4312
XP_005270758                                                           17    4312
NP_002021                                                              16    7355
NP_001269475                                                           16    7355
NP_001269476                                                           16    7355
NP_114406                                                              16    7355

>NP_000224
          Length = 699

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YMLTVITLE 9
           Y LTVITLE
Sbjct: 455 YTLTVITLE 463



>NP_000360
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YMLTVITLE 9
           Y LTVITLE
Sbjct: 510 YTLTVITLE 518



>XP_005268094
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YMLTVITLE 9
           Y LTVITLE
Sbjct: 510 YTLTVITLE 518



>XP_005264366
          Length = 380

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YMLTVITLE 9
           Y LTVITLE
Sbjct: 136 YTLTVITLE 144



>XP_006712078
          Length = 389

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YMLTVITLE 9
           Y LTVITLE
Sbjct: 145 YTLTVITLE 153



>NP_000537
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 251 ILTIITLE 258



>NP_001263689
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 212 ILTIITLE 219



>NP_001119584
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 251 ILTIITLE 258



>NP_001119586
          Length = 341

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 251 ILTIITLE 258



>NP_001263625
          Length = 302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 212 ILTIITLE 219



>NP_001119590
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 212 ILTIITLE 219



>NP_001263690
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 212 ILTIITLE 219



>NP_001119585
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 251 ILTIITLE 258



>NP_001263624
          Length = 307

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 212 ILTIITLE 219



>NP_001119588
          Length = 209

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 119 ILTIITLE 126



>NP_001119587
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 119 ILTIITLE 126



>NP_001119589
          Length = 214

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MLTVITLE 9
           +LT+ITLE
Sbjct: 119 ILTIITLE 126



>NP_001263627
          Length = 182

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  MLTVITLE 9
          +LT+ITLE
Sbjct: 92 ILTIITLE 99



>NP_001263628
          Length = 187

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  MLTVITLE 9
          +LT+ITLE
Sbjct: 92 ILTIITLE 99



>NP_001263626
          Length = 234

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  MLTVITLE 9
          +LT+ITLE
Sbjct: 92 ILTIITLE 99



>NP_001127948
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YMLTVITLE 9
           Y LT ITLE
Sbjct: 278 YFLTHITLE 286



>NP_056165
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YMLTVITLE 9
           Y LT ITLE
Sbjct: 278 YFLTHITLE 286



>XP_005270761
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YMLTVITLE 9
           Y LT ITLE
Sbjct: 278 YFLTHITLE 286



>XP_005270760
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YMLTVITLE 9
           Y LT ITLE
Sbjct: 278 YFLTHITLE 286



>XP_005270759
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YMLTVITLE 9
           Y LT ITLE
Sbjct: 278 YFLTHITLE 286



>XP_006710604
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YMLTVITLE 9
           Y LT ITLE
Sbjct: 278 YFLTHITLE 286



>XP_005270758
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YMLTVITLE 9
           Y LT ITLE
Sbjct: 278 YFLTHITLE 286



>NP_002021
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YMLTVITLE 9
           Y++T+I L+
Sbjct: 114 YLITIIALD 122



>NP_001269475
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YMLTVITLE 9
          Y L ++TLE
Sbjct: 68 YQLKILTLE 76



>NP_001269476
          Length = 435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YMLTVITLE 9
          Y L ++TLE
Sbjct: 63 YQLKILTLE 71



>NP_114406
          Length = 435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YMLTVITLE 9
          Y L ++TLE
Sbjct: 63 YQLKILTLE 71



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.142    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 340,540
Number of extensions: 616
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)