Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              21     229
XP_005262424                                                           21     229
NP_277025                                                              16    5631
NP_001278274                                                           16    5631
NP_277024                                                              16    5631
NP_277022                                                              16    5631
NP_001778                                                              16    5631
NP_277021                                                              16    5631
NP_076916                                                              16    5631
NP_055838                                                              16    5631
NP_277071                                                              16    5631
NP_001263181                                                           16    5631
XP_005252943                                                           16    5631
XP_006711133                                                           16    5631
XP_006711131                                                           16    5631
XP_006711129                                                           16    5631
XP_006711128                                                           16    5631
XP_006711127                                                           16    5631
XP_006711126                                                           16    5631
XP_006711125                                                           16    5631
NP_001180270                                                           16    7355
NP_937784                                                              16    7355
NP_689646                                                              16    7355
NP_940841                                                              16    7355
NP_057717                                                              16    7355
NP_005890                                                              16    7355
NP_114068                                                              16    7355
NP_114064                                                              16    7355
NP_001128627                                                           16    7355
NP_001276907                                                           16    7355
NP_004638                                                              16    7355
NP_001128628                                                           16    7355
XP_005259349                                                           16    7355
XP_005259347                                                           16    7355
XP_006723471                                                           16    7355
XP_005259346                                                           16    7355
XP_006723470                                                           16    7355
XP_006721966                                                           16    7355
XP_005255408                                                           16    7355
XP_005255409                                                           16    7355
XP_006720306                                                           16    7355
XP_006718830                                                           16    7355
XP_005265476                                                           16    7355
NP_006282                                                              16    7355
NP_003232                                                              16    7355
NP_001032360                                                           16    7355
NP_003742                                                              16    7355
NP_065944                                                              15    9605
NP_003875                                                              15    9605
XP_005266713                                                           15    9605
XP_006717897                                                           15    9605
XP_006717896                                                           15    9605
XP_005265585                                                           15    9605
NP_055728                                                              15    9605
>NP_722576
          Length = 3080

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSEEEMVMD 9
            +SEEEMVMD
Sbjct: 2298 ISEEEMVMD 2306
>XP_005262424
          Length = 2875

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSEEEMVMD 9
            +SEEEMVMD
Sbjct: 2093 ISEEEMVMD 2101
>NP_277025
          Length = 565

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 122 VSEEEMSED 130
>NP_001278274
          Length = 772

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 329 VSEEEMSED 337
>NP_277024
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 305 VSEEEMSED 313
>NP_277022
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  VSEEEMVMD 9
          VSEEEM  D
Sbjct: 83 VSEEEMSED 91
>NP_001778
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 352 VSEEEMSED 360
>NP_277021
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 339 VSEEEMSED 347
>NP_076916
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 337 VSEEEMSED 345
>NP_055838
          Length = 676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSEEEMVM 8
           +SE+EMV+
Sbjct: 511 ISEDEMVL 518
>NP_277071
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 327 VSEEEMSED 335
>NP_001263181
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSEEEMVM 8
           +SE+EMV+
Sbjct: 512 ISEDEMVL 519
>XP_005252943
          Length = 483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VSEEEMVM 8
          VSEEEM +
Sbjct: 4  VSEEEMAL 11
>XP_006711133
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 339 VSEEEMSED 347
>XP_006711131
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 295 VSEEEMSED 303
>XP_006711129
          Length = 781

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 338 VSEEEMSED 346
>XP_006711128
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 342 VSEEEMSED 350
>XP_006711127
          Length = 791

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 348 VSEEEMSED 356
>XP_006711126
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 352 VSEEEMSED 360
>XP_006711125
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           VSEEEM  D
Sbjct: 352 VSEEEMSED 360
>NP_001180270
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           V EEE+V+D
Sbjct: 125 VFEEEIVID 133
>NP_937784
          Length = 914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VSEEEMVM 8
           VSEEE+V+
Sbjct: 144 VSEEEVVI 151
>NP_689646
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSEEEMVM 8
           V EEEMV+
Sbjct: 209 VPEEEMVL 216
>NP_940841
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSEEEMVM 8
           V EEEMV+
Sbjct: 209 VPEEEMVL 216
>NP_057717
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  VSEEEMV 7
          VSEE+MV
Sbjct: 32 VSEEDMV 38
>NP_005890
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           ++EEE VM+
Sbjct: 695 IAEEEAVME 703
>NP_114068
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           ++EEE VM+
Sbjct: 695 IAEEEAVME 703
>NP_114064
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           ++EEE VM+
Sbjct: 695 IAEEEAVME 703
>NP_001128627
          Length = 414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 159 LKEEETIMD 167
>NP_001276907
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 159 LKEEETIMD 167
>NP_004638
          Length = 380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 159 LKEEETIMD 167
>NP_001128628
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VSEEEMVMD 9
          + EEE +MD
Sbjct: 77 LKEEETIMD 85
>XP_005259349
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 133 LKEEETIMD 141
>XP_005259347
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 133 LKEEETIMD 141
>XP_006723471
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 133 LKEEETIMD 141
>XP_005259346
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 159 LKEEETIMD 167
>XP_006723470
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSEEEMVMD 9
           + EEE +MD
Sbjct: 133 LKEEETIMD 141
>XP_006721966
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           ++EEE VM+
Sbjct: 625 IAEEEAVME 633
>XP_005255408
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  VSEEEMV 7
          VSEE+MV
Sbjct: 32 VSEEDMV 38
>XP_005255409
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  VSEEEMV 7
          VSEE+MV
Sbjct: 32 VSEEDMV 38
>XP_006720306
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VSEEEMV 7
           VSEEE+V
Sbjct: 113 VSEEELV 119
>XP_006718830
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSEEEMVM 8
           V EEEMV+
Sbjct: 209 VPEEEMVL 216
>XP_005265476
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SEEEMVMD 9
           SEE  VMD
Sbjct: 362 SEERQVMD 369
>NP_006282
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VSEEEMV 7
           VSEEE+V
Sbjct: 113 VSEEELV 119
>NP_003232
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SEEEMVMD 9
           SEE  VMD
Sbjct: 445 SEERQVMD 452
>NP_001032360
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           VSEEE++ D
Sbjct: 163 VSEEELLGD 171
>NP_003742
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           VSEEE++ D
Sbjct: 163 VSEEELLGD 171
>NP_065944
          Length = 1701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSEEEMVMD 9
           ++EE MVM+
Sbjct: 304 INEEAMVMN 312
>NP_003875
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VSEEEM 6
           VSEEEM
Sbjct: 153 VSEEEM 158
>XP_005266713
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSEEEMV 7
           VSEEE++
Sbjct: 756 VSEEELI 762
>XP_006717897
          Length = 1160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VSEEEM 6
           VSEEEM
Sbjct: 442 VSEEEM 447
>XP_006717896
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VSEEEM 6
           VSEEEM
Sbjct: 468 VSEEEM 473
>XP_005265585
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VSEEEM 6
           VSEEEM
Sbjct: 153 VSEEEM 158
>NP_055728
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VSEEEMV 7
           VSEEE++
Sbjct: 756 VSEEELI 762
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.116    0.264 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 663,403
Number of extensions: 867
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package