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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              18    1482
NP_109590                                                              16    5631
NP_071347                                                              16    5631
XP_006713348                                                           16    5631
NP_001273046                                                           16    7355
NP_068597                                                              16    7355
NP_001273047                                                           16    7355
NP_001273048                                                           16    7355
NP_001273045                                                           16    7355
XP_005274216                                                           16    7355
XP_006718717                                                           16    7355
XP_005274213                                                           16    7355
XP_005274211                                                           16    7355
XP_005274209                                                           16    7355
NP_001164009                                                           15    9605
NP_775814                                                              15    9605
XP_006713590                                                           15    9605
XP_006713589                                                           15    9605
XP_005247255                                                           15    9605

>NP_000312
          Length = 928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TIQQLMMSL 9
           TIQQLMM L
Sbjct: 381 TIQQLMMIL 389



>NP_109590
          Length = 1906

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TIQQLMMS 8
           T+QQL++S
Sbjct: 448 TVQQLLLS 455



>NP_071347
          Length = 1314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IQQLMMSL 9
           ++QLMMSL
Sbjct: 378 LKQLMMSL 385



>XP_006713348
          Length = 1314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IQQLMMSL 9
           ++QLMMSL
Sbjct: 378 LKQLMMSL 385



>NP_001273046
          Length = 153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TIQQLMMSL 9
          T+QQLM  L
Sbjct: 10 TVQQLMAHL 18



>NP_068597
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TIQQLMMSL 9
           T+QQLM  L
Sbjct: 111 TVQQLMAHL 119



>NP_001273047
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TIQQLMMSL 9
          T+QQLM  L
Sbjct: 13 TVQQLMAHL 21



>NP_001273048
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TIQQLMMSL 9
          T+QQLM  L
Sbjct: 13 TVQQLMAHL 21



>NP_001273045
          Length = 245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TIQQLMMSL 9
           T+QQLM  L
Sbjct: 102 TVQQLMAHL 110



>XP_005274216
          Length = 153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TIQQLMMSL 9
          T+QQLM  L
Sbjct: 10 TVQQLMAHL 18



>XP_006718717
          Length = 153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TIQQLMMSL 9
          T+QQLM  L
Sbjct: 10 TVQQLMAHL 18



>XP_005274213
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TIQQLMMSL 9
          T+QQLM  L
Sbjct: 13 TVQQLMAHL 21



>XP_005274211
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TIQQLMMSL 9
          T+QQLM  L
Sbjct: 13 TVQQLMAHL 21



>XP_005274209
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TIQQLMMSL 9
           T+QQLM  L
Sbjct: 111 TVQQLMAHL 119



>NP_001164009
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIQQLMM 7
           T+QQL+M
Sbjct: 152 TLQQLLM 158



>NP_775814
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIQQLMM 7
           T+QQL+M
Sbjct: 152 TLQQLLM 158



>XP_006713590
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIQQLMM 7
           T+QQL+M
Sbjct: 152 TLQQLLM 158



>XP_006713589
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIQQLMM 7
           T+QQL+M
Sbjct: 152 TLQQLLM 158



>XP_005247255
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TIQQLMM 7
           T+QQL+M
Sbjct: 180 TLQQLLM 186



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.130    0.299 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 257,946
Number of extensions: 231
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)