Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1135
NP_001254505                                                           18    1482
NP_694942                                                              18    1482
NP_776194                                                              17    4312
NP_079335                                                              17    4312
XP_006715631                                                           17    4312
NP_003244                                                              16    5631
NP_055175                                                              16    5631
XP_005261097                                                           16    5631
XP_005261096                                                           16    5631
XP_005261095                                                           16    5631
XP_005261094                                                           16    5631
NP_006436                                                              16    7355
NP_783165                                                              16    7355
>NP_004251
          Length = 1208

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TEQIAALLR 9
           TE+IAALLR
Sbjct: 713 TERIAALLR 721
>NP_001254505
          Length = 1118

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   TEQIAALLR 9
           TEQ+AAL+R
Sbjct: 144 TEQLAALVR 152
>NP_694942
          Length = 1123

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   TEQIAALLR 9
           TEQ+AAL+R
Sbjct: 144 TEQLAALVR 152
>NP_776194
          Length = 495

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TEQIAALLR 9
           TEQ  ALLR
Sbjct: 163 TEQAVALLR 171
>NP_079335
          Length = 715

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   EQIAALLR 9
           E+IAALLR
Sbjct: 328 EKIAALLR 335
>XP_006715631
          Length = 648

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   EQIAALLR 9
           E+IAALLR
Sbjct: 328 EKIAALLR 335
>NP_003244
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TEQIAALLR 9
            TEQ+AA  R
Sbjct: 999  TEQVAAFCR 1007
>NP_055175
          Length = 239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQIAALLR 9
           EQ+A+LLR
Sbjct: 115 EQLASLLR 122
>XP_005261097
          Length = 1452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TEQIAALLR 9
            TEQ+AA  R
Sbjct: 999  TEQVAAFCR 1007
>XP_005261096
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TEQIAALLR 9
            TEQ+AA  R
Sbjct: 999  TEQVAAFCR 1007
>XP_005261095
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TEQIAALLR 9
            TEQ+AA  R
Sbjct: 999  TEQVAAFCR 1007
>XP_005261094
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TEQIAALLR 9
            TEQ+AA  R
Sbjct: 999  TEQVAAFCR 1007
>NP_006436
          Length = 2335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    EQIAALLR 9
            E++AAL+R
Sbjct: 1843 EEVAALIR 1850
>NP_783165
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EQIAALL 8
          EQ+AALL
Sbjct: 14 EQVAALL 20
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.131    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 316,905
Number of extensions: 564
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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