Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_055853                                                              17    2528
NP_056039                                                              17    3301
NP_001106207                                                           17    3301
XP_005249154                                                           17    3301
XP_005249155                                                           17    3301
XP_005249152                                                           17    3301
XP_006713141                                                           17    3301
XP_006713140                                                           17    3301
XP_005265056                                                           17    3301
NP_061983                                                              17    3301
NP_078787                                                              17    4312
NP_777567                                                              17    4312
NP_003585                                                              16    5631
NP_036533                                                              16    5631
NP_689540                                                              16    5631
XP_005261968                                                           16    5631
XP_005261966                                                           16    5631
XP_005261967                                                           16    5631
XP_006724476                                                           16    5631
XP_005261965                                                           16    5631
XP_006720086                                                           16    5631
XP_006720085                                                           16    5631
XP_006720084                                                           16    5631
XP_005271334                                                           16    5631
XP_006711044                                                           16    5631
XP_006711043                                                           16    5631
XP_006711042                                                           16    5631
NP_705838                                                              16    7355
NP_001121138                                                           16    7355
NP_001121139                                                           16    7355
NP_001121137                                                           16    7355
NP_001121135                                                           16    7355
NP_001121134                                                           16    7355
NP_006793                                                              16    7355
NP_001244959                                                           16    7355
NP_001244958                                                           16    7355
XP_005259437                                                           16    7355
XP_005252002                                                           16    7355
XP_005252001                                                           16    7355
XP_006717142                                                           16    7355
XP_005252000                                                           16    7355
XP_006717141                                                           16    7355
XP_006717140                                                           16    7355
XP_006717139                                                           16    7355
XP_005251997                                                           16    7355
XP_006717138                                                           16    7355
XP_005270447                                                           16    7355
NP_001121136                                                           16    7355
NP_000168                                                              16    7355
NP_937895                                                              16    7355
NP_005041                                                              15    9605
NP_056993                                                              15    9605
NP_055625                                                              15    9605
XP_005268010                                                           15    9605
XP_005268011                                                           15    9605
XP_005268009                                                           15    9605
XP_005268008                                                           15    9605
XP_005268003                                                           15    9605
XP_005268006                                                           15    9605
XP_005267999                                                           15    9605
XP_005267997                                                           15    9605
XP_005267998                                                           15    9605
XP_005267996                                                           15    9605
XP_006720286                                                           15    9605
XP_006711734                                                           15    9605
XP_006711733                                                           15    9605
XP_006711732                                                           15    9605
XP_006711731                                                           15    9605
XP_006711730                                                           15    9605
XP_006711729                                                           15    9605
XP_005245695                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    EKESTSAL 8
            EKESTSAL
Sbjct: 1379 EKESTSAL 1386
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    EKESTSAL 8
            EKESTSAL
Sbjct: 1174 EKESTSAL 1181
>NP_055853
          Length = 1427

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EKESTSALT 9
           +KES+SALT
Sbjct: 168 KKESSSALT 176
>NP_056039
          Length = 1233

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKESTSALT 9
           E+ STSALT
Sbjct: 712 EQHSTSALT 720
>NP_001106207
          Length = 1512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    EKESTSALT 9
            E+ STSALT
Sbjct: 1149 EQHSTSALT 1157
>XP_005249154
          Length = 442

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EKESTSALT 9
          EKE  SALT
Sbjct: 28 EKEEASALT 36
>XP_005249155
          Length = 442

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EKESTSALT 9
          EKE  SALT
Sbjct: 28 EKEEASALT 36
>XP_005249152
          Length = 545

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EKESTSALT 9
          EKE  SALT
Sbjct: 28 EKEEASALT 36
>XP_006713141
          Length = 1274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EKESTSALT 9
           E+ STSALT
Sbjct: 753 EQHSTSALT 761
>XP_006713140
          Length = 1629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    EKESTSALT 9
            E+ STSALT
Sbjct: 1108 EQHSTSALT 1116
>XP_005265056
          Length = 1670

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    EKESTSALT 9
            E+ STSALT
Sbjct: 1149 EQHSTSALT 1157
>NP_061983
          Length = 545

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EKESTSALT 9
          EKE  SALT
Sbjct: 28 EKEEASALT 36
>NP_078787
          Length = 603

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   EKESTSALT 9
           E++ST+ALT
Sbjct: 207 EEQSTAALT 215
>NP_777567
          Length = 417

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           EKES  ALT
Sbjct: 326 EKESDDALT 334
>NP_003585
          Length = 1162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKESTSALT 9
           EKE ++ALT
Sbjct: 621 EKEKSTALT 629
>NP_036533
          Length = 1838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EKE T A+T
Sbjct: 1610 EKERTKAIT 1618
>NP_689540
          Length = 723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EKESTSALT 9
          E+E T+ALT
Sbjct: 3  EEEETAALT 11
>XP_005261968
          Length = 1838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EKE T A+T
Sbjct: 1610 EKERTKAIT 1618
>XP_005261966
          Length = 1838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EKE T A+T
Sbjct: 1610 EKERTKAIT 1618
>XP_005261967
          Length = 1838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EKE T A+T
Sbjct: 1610 EKERTKAIT 1618
>XP_006724476
          Length = 1838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EKE T A+T
Sbjct: 1610 EKERTKAIT 1618
>XP_005261965
          Length = 1920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EKE T A+T
Sbjct: 1692 EKERTKAIT 1700
>XP_006720086
          Length = 703

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EKESTSALT 9
          E+E T+ALT
Sbjct: 3  EEEETAALT 11
>XP_006720085
          Length = 704

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EKESTSALT 9
          E+E T+ALT
Sbjct: 3  EEEETAALT 11
>XP_006720084
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EKESTSALT 9
          E+E T+ALT
Sbjct: 3  EEEETAALT 11
>XP_005271334
          Length = 1161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKESTSALT 9
           EKE ++ALT
Sbjct: 620 EKEKSTALT 628
>XP_006711044
          Length = 1168

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKESTSALT 9
           EKE ++ALT
Sbjct: 627 EKEKSTALT 635
>XP_006711043
          Length = 1169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKESTSALT 9
           EKE ++ALT
Sbjct: 628 EKEKSTALT 636
>XP_006711042
          Length = 1169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKESTSALT 9
           EKE ++ALT
Sbjct: 628 EKEKSTALT 636
>NP_705838
          Length = 4069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKESTSALT 9
            E+E T+ALT
Sbjct: 1183 EQEPTAALT 1191
>NP_001121138
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>NP_001121139
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>NP_001121137
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 666 EEEKTEALT 674
>NP_001121135
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 702 EEEKTEALT 710
>NP_001121134
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 666 EEEKTEALT 674
>NP_006793
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KESTSALT 9
           KE++SALT
Sbjct: 231 KETSSALT 238
>NP_001244959
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 674 EEEKTEALT 682
>NP_001244958
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 683 EEEKTEALT 691
>XP_005259437
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EKESTSALT 9
          EKES  ALT
Sbjct: 15 EKESGMALT 23
>XP_005252002
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 666 EEEKTEALT 674
>XP_005252001
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>XP_006717142
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>XP_005252000
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>XP_006717141
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>XP_006717140
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>XP_006717139
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 677 EEEKTEALT 685
>XP_005251997
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 687 EEEKTEALT 695
>XP_006717138
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 755 EEEKTEALT 763
>XP_005270447
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KESTSALT 9
           KE++SALT
Sbjct: 178 KETSSALT 185
>NP_001121136
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 666 EEEKTEALT 674
>NP_000168
          Length = 782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 717 EEEKTEALT 725
>NP_937895
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EKESTSALT 9
           E+E T ALT
Sbjct: 666 EEEKTEALT 674
>NP_005041
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 549 EATSALT 555
>NP_056993
          Length = 2371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKESTSALT 9
            EK+S SAL+
Sbjct: 1562 EKQSPSALS 1570
>NP_055625
          Length = 3117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1596 EKDSTSIAT 1604
>XP_005268010
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268011
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268009
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268008
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268003
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 390 EATSALT 396
>XP_005268006
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 390 EATSALT 396
>XP_005267999
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_005267997
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_005267998
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_005267996
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_006720286
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESTSALT 9
           E+TSALT
Sbjct: 462 EATSALT 468
>XP_006711734
          Length = 3136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1574 EKDSTSIAT 1582
>XP_006711733
          Length = 3137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1575 EKDSTSIAT 1583
>XP_006711732
          Length = 3154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1592 EKDSTSIAT 1600
>XP_006711731
          Length = 3157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1595 EKDSTSIAT 1603
>XP_006711730
          Length = 3157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1595 EKDSTSIAT 1603
>XP_006711729
          Length = 3158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1596 EKDSTSIAT 1604
>XP_005245695
          Length = 3158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKESTSALT 9
            EK+STS  T
Sbjct: 1596 EKDSTSIAT 1604
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.271   0.0902    0.188 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 451,356
Number of extensions: 509
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.4 bits)
S2: 28 (15.4 bits)

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