Primary information |
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CancerPPD ID | 3602 |
PMID | 22100226 |
YEAR | 2012 |
SEQUENCE | GFGMALKLLKKVL |
LENGTH | 13 |
NAME | MAC1 |
C-ter Modification | Amidation |
N-ter Modification | Free |
Linear/Cyclic | Linear |
L/D/Mix | L |
Non-Natural | None |
NATURE | Antimicrobial and Antifungal |
ACTIVITY | IC50 = 23±4 µM |
SOURCE | Macropins and their analogs |
Cancer Type | Colon Cancer |
ASSAY | MTT/MTS assay |
Patent ID | None |
Tissue | Colon |
CELL LINE | SW |
TEST TIME | 48-h |
Secondary information |
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STRUCTURE | |
DSSP states | CCSTTHHHHTTTC |
SMILES | NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N |
External Links |
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PDB exact | PDB partial | SP exact | SP partial | TrEMBL exact | TrEMBL partial | IEDB exact | IEDB partial |
NA | NA | NA | NA | NA | NA | NA | NA |
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