Welcome to Entry Card of Peptide


Details of CancerPDF_ID CancerPDF_ID1071
Primary information
CancerPDF_IDCancerPDF_ID1071
PMID16395409
Peptide SequenceNVHSAGAAGSRMNFRPGVLSS
Peptide Sequence in Publication(R) NVHSAGAAGSRMNFRPGVLSS (R)
Protein NamePRO1851(ITIH4 splice variant)
UniprotKB Entry NameNA
BiofluidSerum
M/Z2115.01
Charge1
Mass/H+NA
Mass (in Daltons)NA
Profiling TechniqueMALDI-TOF
Peptide Identification TechniqueQ/TOF/TOF and LC-MS/MS
Quantification TechniqueNA
LabelingLabel Free
FDRless than 1 × 10–5
p-Value5.82E-18
SoftwareMASCOT (v 2.0.04 for Windows)
Length of Peptide21
Cancer Type"Advanced Prostate, Breast and Bladder cancer"
Database for Peptide searchNCBI refseq Protein Database
ModificationNA
Number of Patients "Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy in training test set, In validation set 41 independent serum samples from patients with advanced prostate cancer (prostate 2 [PR2])"
Regulation/Differential Expression"Upregulated in cancer vs normal with Ratio of median intensity (patients/Controls) =3.22, 12.23 and 10.61 in prostate, bladder and breast cancer respectively"
ValidationIndependent validation
Sensitivity97.5% for multiclass and 100 % for binary classification system on independent validation dataset
SpecificityNA
Accuracy97.5 % on validation dataset
Secondary information
Peptide AtlasNA
IEDB