Welcome to Entry Card of Peptide


Details of CancerPDF_ID CancerPDF_ID1068
Primary information
CancerPDF_IDCancerPDF_ID1068
PMID16395409
Peptide SequenceQLGLPGPPDVPDHAAYHPFR
Peptide Sequence in PublicationQLGLPGPPDVPDHAAYHPFR
Protein NameInter-alpha-trypsin inhibitor heavy chain H13
UniprotKB Entry NameITIH4_HUMAN
BiofluidSerum
M/Z2183.91
Charge1
Mass/H+NA
Mass (in Daltons)NA
Profiling TechniqueMALDI-TOF
Peptide Identification TechniqueQ/TOF/TOF and LC-MS/MS
Quantification TechniqueNA
LabelingLabel Free
FDRless than 1 × 10–5
p-Value9.87E-11
SoftwareMASCOT (v 2.0.04 for Windows)
Length of Peptide20
Cancer Type"Advanced Prostate, Breast and Bladder cancer"
Database for Peptide searchNCBI refseq Protein Database
ModificationNA
Number of Patients "Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy in training test set, In validation set 41 independent serum samples from patients with advanced prostate cancer (prostate 2 [PR2])"
Regulation/Differential Expression"Upregulated in cancer vs normal with Ratio of median intensity (patients/Controls) =1.71, 1.79 and 2.83 in prostate, bladder and breast cancer respectively"
ValidationIndependent validation
Sensitivity97.5% for multiclass and 100 % for binary classification system on independent validation dataset
SpecificityNA
Accuracy97.5 % on validation dataset
Secondary information
Peptide AtlasPeptideAtlas
IEDB