Welcome to Entry Card of Peptide


Details of CancerPDF_ID CancerPDF_ID1060
Primary information
CancerPDF_IDCancerPDF_ID1060
PMID16395409
Peptide SequenceGLPGPPDVPDHAAYHPF
Peptide Sequence in PublicationGLPGPPDVPDHAAYHPF
Protein NameInter-alpha-trypsin inhibitor heavy chain H5
UniprotKB Entry NameITIH4_HUMAN
BiofluidSerum
M/Z1786.86
Charge1
Mass/H+NA
Mass (in Daltons)NA
Profiling TechniqueMALDI-TOF
Peptide Identification TechniqueQ/TOF/TOF and LC-MS/MS
Quantification TechniqueNA
LabelingLabel Free
FDRless than 1 × 10–5
p-Valueless than 0.01
SoftwareMASCOT (v 2.0.04 for Windows)
Length of Peptide17
Cancer Type"Advanced Prostate, Breast and Bladder cancer"
Database for Peptide searchNCBI refseq Protein Database
ModificationNA
Number of Patients "Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy in training test set, In validation set 41 independent serum samples from patients with advanced prostate cancer (prostate 2 [PR2])"
Regulation/Differential Expression"Upregulated in cancer vs normal with Ratio of median intensity (patients/Controls) =2.39, 2.88 and 2.3 in prostate, bladder and breast cancer respectively"
ValidationIndependent validation
Sensitivity97.5% on independent validation dataset
SpecificityNA
Accuracy97.5 % on validation dataset
Secondary information
Peptide AtlasPeptideAtlas
IEDB