Welcome to Entry Card of Peptide


Details of CancerPDF_ID CancerPDF_ID1037
Primary information
CancerPDF_IDCancerPDF_ID1037
PMID16395409
Peptide SequenceDEAGSEADHEGTHSTKRGHAKSRPV
Peptide Sequence in PublicationDEAGSEADHEGTHSTKRGHAKSRPV (R)
Protein NameFibrinogen alpha chain
UniprotKB Entry NameFIBA_HUMAN
BiofluidSerum
M/Z2659.03
Charge1
Mass/H+NA
Mass (in Daltons)NA
Profiling TechniqueMALDI-TOF
Peptide Identification TechniqueQ/TOF/TOF and LC-MS/MS
Quantification TechniqueNA
LabelingLabel Free
FDRless than 1 × 10–5
p-Value3.78E-08
SoftwareMASCOT (v 2.0.04 for Windows)
Length of Peptide25
Cancer Type"Advanced Prostate, Breast and Bladder cancer"
Database for Peptide searchNCBI refseq Protein Database
ModificationNA
Number of Patients "Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy"
Regulation/Differential Expression"Upregulated in cancer vs normal with Ratio of median intensity (patients/Controls) = 1.37, 1.18 and 2.45 in prostate, bladder and breast cancer respectively"
ValidationIndependent validation
Sensitivity97.5% on independent validation dataset
SpecificityNA
Accuracy97.5 % on validation dataset
Secondary information
Peptide AtlasNA
IEDB