| Primary information |
|---|
| sequence ID | Seq_9972 |
| Peptide sequence | YYLQGAKIPKPEASFSPR |
| CancerPDF_ID | CancerPDF_ID61, CancerPDF_ID1861, CancerPDF_ID3031, CancerPDF_ID12733, |
| PMID | 16896061,21136997,21136997,27058005 |
| Protein Name | Inter-alpha-trypsin inhibitor heavy chain H19,Inter-alpha-trypsin inhibitor heavy chain H4,Inter-alpha-trypsin inhibitor heavy chain H4,Inter-alpha-trypsin inhibitor heavy chain H5 |
| UniprotKB Entry Name | ITIH4_HUMAN,ITIH4_HUMAN,ITIH4_HUMAN,ITIH5_HUMAN |
| Fluid | Serum,Serum,Plasma,Serum |
| M/Z | 684.63,2051.08401,2051.084,2051.125 |
| Charge | 1,1,1,NA |
| Mass (in Da) | 2052.08,NA,NA,NA |
| fdr | NA,NA,NA,NA |
| Profiling Technique | MALDI-TOF,LC-MS,LC-MS,MALDI-TOF |
| Peptide Identification technique | Q/TOF MS/MS,LC-MS-MS/MS,LC-MS-MS/MS,LC-MS/MS |
| Quantification Technique | NA,LC-ESI-MS,LC-ESI-MS,NA |
| Labelled/Label Free | Label Free,Label Free,Label Free,Label Free |
| FDR | NA,NA,NA,NA |
| CancerPDF_ID | CancerPDF_ID61, CancerPDF_ID1861, CancerPDF_ID3031, CancerPDF_ID12733, |
| p-Value | 1.00E-05,NA,NA,"less than 0.05,0.763,0.582" |
| Software | MASCOT,MASCOT(v. 2.2.01),MASCOT(v. 2.2.01),Proteome Discoverer |
| Length | 18,18,18,18 |
| Cancer Type | Metastatic thyroid carcinomas,Colorectal cancer,Normal,Breast cancer |
| Database | NCBI refseq Protein Database,SwissProt Database,SwissProt Database,SwissProt Database |
| Modification | NA,NA,NA,NA |
| Number of Patients | 40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation,30 patients and 30 healthy controls,27 healthy individuals," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)." |
| Regulation | NA,NA,NA,"Upregulated with the fold change of 0.80 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 1.02, Upregulated in BC vs healthy with 1.047 fold change" |
| Validation | Independent validation,Leave One out Cross validation,Leave One out Cross validation,NA |
| Sensitivity | 95% on independent dataset,NA,NA,NA |
| Specificity | 95% on independent dataset,NA,NA,NA |
| Accuracy | NA,NA,NA,NA |
| Peptide Atlas | NA |
| IEDB | |