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Details of CancerPDF entry with Sequence VLSPADKTNVKAAWGKVGAHAGEYGAEALERm
Primary information
sequence IDSeq_9169
Peptide sequenceVLSPADKTNVKAAWGKVGAHAGEYGAEALERM
CancerPDF_ID CancerPDF_ID241, CancerPDF_ID10701,
PMID19728888,21805675
Protein NameHemoglobin alpha,Hemoglobin subunit alpha
UniprotKB Entry NameHBA_HUMAN,HBA_HUMAN
FluidSerum,Urine
M/Z3326.6863,3326.7238
ChargeNA,NA
Mass (in Da)NA,NA
fdrNA,NA
Profiling TechniqueMALDI-TOF,MALDI-TOF
Peptide Identification techniqueLC-MS/MS,MALDI-TOF-MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDRNA,1
CancerPDF_ID CancerPDF_ID241, CancerPDF_ID10701,
p-Valueless than 0.01,NA
SoftwareMASCOT(v 2.0.04 for Windows),NA
Length32,32
Cancer Type"Non-small cell lung cancer (NSCLC) patients, who were treated with first-line chemotherapy",Muscle-invasive bladder cancer
DatabaseSwissProt Database (release 54.7),SwissProt Database
ModificationNA,NA
Number of Patients"27 patients, 13 normal individuals",751 bladder cancer and 127 control
RegulationSignature peptide that can Differentiate between NSCLC patients and healthy volunteers,Differentially expressed between cancer vs normal samples
ValidationIndependent validation,Mann-Whitney tests and areas under receiver-operator characteristic
Sensitivity1,NA
Specificity0.96,NA
Accuracy0.98,NA
Peptide AtlasNA
IEDB
Primary information
sequence IDSeq_9171
Peptide sequenceVLSPADKTNVKAAWGKVGAHAGEYGAEALERm
CancerPDF_ID CancerPDF_ID3512, CancerPDF_ID3800, CancerPDF_ID3806,
PMID27026199,27026199,27026199
Protein NameHemoglobin subunit alpha,Hemoglobin subunit alpha,Hemoglobin subunit alpha
UniprotKB Entry NameHBA_HUMAN,HBA_HUMAN,HBA_HUMAN
FluidUrine,Urine,Urine
M/ZNA,NA,NA
ChargeNA,NA,NA
Mass (in Da)NA,NA,NA
fdr3341.69,3341.68,3341.7
Profiling Technique"CE-MS, Micro-TOF-MS","CE-MS, Micro-TOF-MS","CE-MS, Micro-TOF-MS"
Peptide Identification techniqueMS-MS,MS-MS,MS-MS
Quantification TechniqueNA,NA,NA
Labelled/Label FreeLabel Free,Label Free,Label Free
FDRNA,NA,NA
CancerPDF_ID CancerPDF_ID3512, CancerPDF_ID3800, CancerPDF_ID3806,
p-Valueless than 0.05,less than 0.01,less than 0.01
SoftwareProteome Discoverer 1.2,Proteome Discoverer 1.2,Proteome Discoverer 1.2
Length32,32,32
Cancer TypeBladder cancer,Bladder cancer,Bladder cancer
DatabaseUniprot Human non-redundant Database,Uniprot Human non-redundant Database,Uniprot Human non-redundant Database
Modificationm: Oxidized-Methionine,m:Oxidized Methionine,m:Oxidized-Methionine
Number of Patients451 for training (341 patients and 110 normal) and 270 for testing(168 primary UBC patients and 102 normal controls);, 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls), 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls)
RegulationDifferentially expressed between primary UBC and normal individual,Differentially expressed between recurrence of UBC vs recurrence control,Differentially expressed between recurrence of UBC vs recurrence control
ValidationIndependent Validation,Independent Validation,Independent Validation
SensitivityFor testing dataset 91%,For testing dataset 88%,For testing dataset 88%
SpecificityFor testing dataset 68%,For testing dataset 51%,For testing dataset 51%
AccuracyFor testing dataset 76%,NA,NA
Peptide AtlasNA
IEDB