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Details of CancerPDF entry with Sequence SSYSKQFTSSTSYNRGDSTFE
Primary information
sequence IDSeq_7752
Peptide sequenceSSYSKQFTSSTSYNRGDSTFE
CancerPDF_ID CancerPDF_ID17, CancerPDF_ID1034,
PMID16896061,16395409
Protein NameFibrinogen alpha chain,Fibrinogen alpha chain
UniprotKB Entry NameFIBA_HUMAN,FIBA_HUMAN
FluidSerum,Serum
M/Z2379.03,2379.03
Charge1,1
Mass (in Da)2379.03,NA
fdrNA,NA
Profiling TechniqueMALDI-TOF,MALDI-TOF
Peptide Identification techniqueQ/TOF MS/MS,Q/TOF/TOF and LC-MS/MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDRNA,less than 1 “5
CancerPDF_ID CancerPDF_ID17, CancerPDF_ID1034,
p-Value1.00E-05,1.54E-16
SoftwareMASCOT,MASCOT (v 2.0.04 for Windows)
Length21,21
Cancer TypeMetastatic thyroid carcinomas,"Advanced Prostate, Breast and Bladder cancer"
DatabaseNCBI refseq Protein Database,NCBI refseq Protein Database
ModificationNA,NA
Number of Patients40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation,"Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy"
RegulationNA,"For bladder (Lower) and for breast (Higher) Differential ion intensity in cancer compare to normal with Ratio of median intensity (patients/Controls) = 1.57, 0.22 and 1.71 in prostate, bladder and breast cancer respectively"
ValidationIndependent validation,Independent validation
Sensitivity95% on independent dataset,97.5% on independent validation dataset
Specificity95% on independent dataset,NA
AccuracyNA,97.5 % on validation dataset
Peptide AtlasNA
IEDB