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Details of CancerPDF entry with Sequence SSYSKQFTSSTSYN
Primary information
sequence IDSeq_7747
Peptide sequenceSSYSKQFTSSTSYN
CancerPDF_ID CancerPDF_ID526, CancerPDF_ID1240, CancerPDF_ID9734, CancerPDF_ID12299,
PMID19795908,21136997,21533267,26992070
Protein NameFibrinogen alpha chain,Fibrinogen alpha,Fibrinogen alpha chain,Fibrinogen alpha chain
UniprotKB Entry NameFIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN
FluidPlasma,Serum,Serum,Serum
M/Z793.85,1585.68963,793.85,1585.6896
Charge2,1,2,NA
Mass (in Da)NA,NA,NA,1586.693529
fdrNA,NA,NA,NA
Profiling TechniqueLC-MS,LC-MS,LC-MS,LC-MS
Peptide Identification techniqueMALDI-TOF/TOF,LC-MS-MS/MS,LC/MS/MS,LC-MS/MS
Quantification TechniqueLC-MRM (multiple reaction monitoring),LC-ESI-MS,Multiple Reaction Monitoring,NA
Labelled/Label FreeLabelled,Label Free,Label Free,Label Free
FDRless than 7%,NA,1.49,FDR 1 %
CancerPDF_ID CancerPDF_ID526, CancerPDF_ID1240, CancerPDF_ID9734, CancerPDF_ID12299,
p-ValueNA,4.80E-05,NA,NA
SoftwareFlexAnalysis 3.0 and Biotools 3.0 software,MASCOT(v. 2.2.01),MASCOT,SEQUEST and Maxquant
Length14,14,14,14
Cancer TypeDuctal adenocarcinoma of the pancreas (DAP),Colorectal cancer,Lung adenocarcinoma,Melanoma
DatabaseNCBI refseq Protein Database,SwissProt Database,Swissprot Database (57.4),SwissProt Database
ModificationNA,NA,NA,NA
Number of Patients"42 normal, 28patients",30 patients and 30 healthy controls,62 lung adenocarcinoma and 30 healthy control,8 cancer samples and 4 healthy samples
RegulationNA,Differentially expressed between cancer vs normal,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal","Present in 4 cancer samples out of 8 cancer samples. ,Present in 1 healthy samples out of 4 healthy samples."
ValidationNA,Leave One out Cross validation,MRM-based validation of 19 candidates,na
SensitivityNA,0.898,NA,NA
SpecificityNA,0.946,NA,NA
AccuracyNA,NA,NA,NA
Peptide AtlasNA
IEDB153467