| Primary information |
|---|
| sequence ID | Seq_7711 |
| Peptide sequence | SSSYSKQFTSSTSYNRGDST |
| CancerPDF_ID | CancerPDF_ID1252, CancerPDF_ID2374, CancerPDF_ID9697, CancerPDF_ID12291, |
| PMID | 21136997,21136997,21533267,26992070 |
| Protein Name | Fibrinogen alpha,Fibrinogen alpha,Fibrinogen alpha chain,Fibrinogen alpha chain |
| UniprotKB Entry Name | FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN |
| Fluid | Serum,Plasma,Serum,Serum |
| M/Z | 2188.95088,2188.9509,730.66,NA |
| Charge | 1,1,3,NA |
| Mass (in Da) | NA,NA,NA,2189.954563 |
| fdr | NA,NA,NA,NA |
| Profiling Technique | LC-MS,LC-MS,LC-MS,LC-MS |
| Peptide Identification technique | LC-MS-MS/MS,LC-MS-MS/MS,LC/MS/MS,LC-MS/MS |
| Quantification Technique | LC-ESI-MS,LC-ESI-MS,Multiple Reaction Monitoring,NA |
| Labelled/Label Free | Label Free,Label Free,Label Free,Label Free |
| FDR | 0.001,NA,1.49,FDR 1 % |
| CancerPDF_ID | CancerPDF_ID1252, CancerPDF_ID2374, CancerPDF_ID9697, CancerPDF_ID12291, |
| p-Value | 7.92E-05,NA,NA,NA |
| Software | MASCOT(v. 2.2.01),MASCOT(v. 2.2.01),MASCOT,SEQUEST and Maxquant |
| Length | 20,20,20,20 |
| Cancer Type | Colorectal cancer,Normal,Lung adenocarcinoma,Melanoma |
| Database | SwissProt Database,SwissProt Database,Swissprot Database (57.4),SwissProt Database |
| Modification | NA,NA,NA,NA |
| Number of Patients | 30 patients and 30 healthy controls,27 healthy individuals,62 lung adenocarcinoma and 30 healthy control,8 cancer samples and 4 healthy samples |
| Regulation | Differentially expressed between cancer vs normal,NA,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal","Present in 6 cancer samples out of 8 cancer samples. ,Present in 1 healthy samples out of 4 healthy samples." |
| Validation | Leave One out Cross validation,Leave One out Cross validation,MRM-based validation of 19 candidates,na |
| Sensitivity | 0.898,NA,NA,NA |
| Specificity | 0.946,NA,NA,NA |
| Accuracy | 0.917,NA,NA,NA |
| Peptide Atlas | PeptideAtlas |
| IEDB | |