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Details of CancerPDF entry with Sequence SSSYSKQFTSSTS
Primary information
sequence IDSeq_7706
Peptide sequenceSSSYSKQFTSSTS
CancerPDF_ID CancerPDF_ID1312, CancerPDF_ID12286, CancerPDF_ID12721,
PMID21136997,26992070,27058005
Protein NameFibrinogen alpha,Fibrinogen alpha chain,Fibrinogen alpha chain
UniprotKB Entry NameFIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN
FluidSerum,Serum,Serum
M/Z1395.6154,1395.6154,1396.795
Charge1,NA,NA
Mass (in Da)NA,1396.624071,NA
fdrNA,NA,NA
Profiling TechniqueLC-MS,LC-MS,MALDI-TOF
Peptide Identification techniqueLC-MS-MS/MS,LC-MS/MS,LC-MS/MS
Quantification TechniqueLC-ESI-MS,NA,NA
Labelled/Label FreeLabel Free,Label Free,Label Free
FDRNA,FDR 1 %,NA
CancerPDF_ID CancerPDF_ID1312, CancerPDF_ID12286, CancerPDF_ID12721,
p-ValueNA,NA,"less than 0.01,0.843,0.629"
SoftwareMASCOT(v. 2.2.01),SEQUEST and Maxquant,Proteome Discoverer
Length13,13,13
Cancer TypeColorectal cancer,Melanoma,Breast cancer
DatabaseSwissProt Database,SwissProt Database,SwissProt Database
ModificationNA,NA,NA
Number of Patients30 patients and 30 healthy controls,8 cancer samples and 4 healthy samples," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)."
RegulationNA,"Present in 8 cancer samples out of 8 cancer samples. ,Present in 4 healthy samples out of 4 healthy samples.","Upregulated with the fold change of 0.57 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 1.01, Upregulated in BC vs healthy with 0.963 fold change"
ValidationLeave One out Cross validation,na,NA
SensitivityNA,NA,NA
SpecificityNA,NA,NA
AccuracyNA,NA,NA
Peptide AtlasNA
IEDB153467