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Details of CancerPDF entry with Sequence SSKITHRIHWESASL
Primary information
sequence IDSeq_7645
Peptide sequenceSSKITHRIHWESASL
CancerPDF_ID CancerPDF_ID33, CancerPDF_ID1049,
PMID16896061,16395409
Protein NameComplement C3f,Complement C3f
UniprotKB Entry NameCO3_HUMAN,CO3_HUMAN
FluidSerum,Serum
M/Z1751.88,1751.88
Charge1,1
Mass (in Da)1751.91,NA
fdrNA,NA
Profiling TechniqueMALDI-TOF,MALDI-TOF
Peptide Identification techniqueQ/TOF MS/MS,Q/TOF/TOF and LC-MS/MS
Quantification TechniqueNA,NA
Labelled/Label FreeLabel Free,Label Free
FDRNA,less than 1 “5
CancerPDF_ID CancerPDF_ID33, CancerPDF_ID1049,
p-Value1.00E-05,9.48E-13
SoftwareMASCOT,MASCOT (v 2.0.04 for Windows)
Length15,15
Cancer TypeMetastatic thyroid carcinomas,"Advanced Prostate, Breast and Bladder cancer"
DatabaseNCBI refseq Protein Database,NCBI refseq Protein Database
ModificationNA,NA
Number of Patients40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation,"Advanced prostate (n = 32), breast (n = 21), and bladder (n = 20) cancer, 33 healthy"
RegulationNA,"Upregulated in cancer vs normal with Ratio of median intensity (patients/Controls) =1.82, 5.7 and 1.36 in prostate, bladder and breast cancer respectively"
ValidationIndependent validation,Independent validation
Sensitivity95% on independent dataset,97.5% on independent validation dataset
Specificity95% on independent dataset,NA
AccuracyNA,97.5 % on validation dataset
Peptide AtlasNA
IEDB533899