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Details of CancerPDF entry with Sequence SEETKENEGFTVTAEGK
Primary information
sequence IDSeq_6976
Peptide sequenceSEETKENEGFTVTAEGK
CancerPDF_ID CancerPDF_ID942, CancerPDF_ID1468, CancerPDF_ID2705, CancerPDF_ID8556, CancerPDF_ID9605, CancerPDF_ID12169,
PMID19795908,21136997,21136997,23667664,21533267,26992070
Protein NameComplement C3,Complement C3,Complement C3,Complement C3f,Complement C3,Complement C3
UniprotKB Entry NameCO3_HUMAN,CO3_HUMAN,CO3_HUMAN,CO3_HUMAN,CO3_HUMAN,CO3_HUMAN
FluidPlasma,Serum,Plasma,Serum,Serum,Serum
M/Z"928.42, 619.28",1854.84832,1854.8483,1854.85,619.27,1854.8483
Charge"2, 3",1,1,1,3,NA
Mass (in Da)NA,NA,NA,1856.94,NA,1855.854099
fdrNA,NA,NA,NA,NA,NA
Profiling TechniqueLC-MS,LC-MS,LC-MS,MALDI-TOF,LC-MS,LC-MS
Peptide Identification techniqueMALDI-TOF/TOF,LC-MS-MS/MS,LC-MS-MS/MS,FT-ICR MS/MS + nano-HPLC,LC/MS/MS,LC-MS/MS
Quantification TechniqueLC-MRM (multiple reaction monitoring),LC-ESI-MS,LC-ESI-MS,NA,Multiple Reaction Monitoring,NA
Labelled/Label FreeLabelled,Label Free,Label Free,Label Free,Label Free,Label Free
FDRless than 7%,NA,NA,NA,1.49,FDR 1 %
CancerPDF_ID CancerPDF_ID942, CancerPDF_ID1468, CancerPDF_ID2705, CancerPDF_ID8556, CancerPDF_ID9605, CancerPDF_ID12169,
p-ValueNA,NA,NA,NA,NA,NA
SoftwareFlexAnalysis 3.0 and Biotools 3.0 software,MASCOT(v. 2.2.01),MASCOT(v. 2.2.01),MASCOT,MASCOT,SEQUEST and Maxquant
Length17,17,17,17,17,17
Cancer TypeDuctal adenocarcinoma of the pancreas (DAP),Colorectal cancer,Normal,"Breast cancer, Lung cancer, Rectal cancer",Lung adenocarcinoma,Melanoma
DatabaseNCBI refseq Protein Database,SwissProt Database,SwissProt Database,NA,Swissprot Database (57.4),SwissProt Database
ModificationNA,NA,NA,NA,NA,NA
Number of Patients"42 normal, 28 patients",30 patients and 30 healthy controls,27 healthy individuals,"Breast Cancer =84, lung cancer= 70, Rectal cancer = 30patients; 500 healthy",62 lung adenocarcinoma and 30 healthy control,8 cancer samples and 4 healthy samples
RegulationNA,NA,NA,NA,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal","Present in 6 cancer samples out of 8 cancer samples. ,Present in 2 healthy samples out of 4 healthy samples."
ValidationNA,Leave One out Cross validation,Leave One out Cross validation,NA,MRM-based validation of 19 candidates,na
SensitivityNA,NA,NA,NA,NA,NA
SpecificityNA,NA,NA,NA,NA,NA
AccuracyNA,NA,NA,NA,NA,NA
Peptide AtlasPeptideAtlas
IEDB