| Primary information |
|---|
| sequence ID | Seq_6679 |
| Peptide sequence | RPHFFFPKSRIV |
| CancerPDF_ID | CancerPDF_ID90, CancerPDF_ID9470, CancerPDF_ID12718, |
| PMID | 16896061,26379225,27058005 |
| Protein Name | CLUSTERIN precursor,Clusterin,Clusterin |
| UniprotKB Entry Name | CLUS_HUMAN,CLUS_HUMAN,CLUS_HUMAN |
| Fluid | Serum,Plasma,Serum |
| M/Z | 1530.86,1530.86,1530.912 |
| Charge | 1,NA,NA |
| Mass (in Da) | 1530.86,NA,NA |
| fdr | NA,NA,NA |
| Profiling Technique | MALDI-TOF,MALDI-TOF,MALDI-TOF |
| Peptide Identification technique | Q/TOF MS/MS,MALDI-TOF/TOF,LC-MS/MS |
| Quantification Technique | NA,NA,NA |
| Labelled/Label Free | Label Free,Label Free,Label Free |
| FDR | NA,NA,NA |
| CancerPDF_ID | CancerPDF_ID90, CancerPDF_ID9470, CancerPDF_ID12718, |
| p-Value | 1.00E-05,NA,"less than 0.05,0.335,0.564" |
| Software | MASCOT,MASCOT (v 2.3),Proteome Discoverer |
| Length | 12,12,12 |
| Cancer Type | Metastatic thyroid carcinomas,Colorectal cancer,Breast cancer |
| Database | NCBI refseq Protein Database,UniprotKB,SwissProt Database |
| Modification | NA,NA,NA |
| Number of Patients | 40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation,"94 patients with CRC, 23 with liver metastasis from CRC (histologically defined) and 34 subjects, which underwent colonoscopy and resulted negative"," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)." |
| Regulation | NA,Lower intensity in liver metastasis than control groups and an opposite trend in adenoma and CRC group.,"Upregulated with the fold change of 0.26 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 1.16, Upregulated in BC vs healthy with 1.106 fold change" |
| Validation | Independent validation,NA,NA |
| Sensitivity | 95% on independent dataset,NA,NA |
| Specificity | 95% on independent dataset,NA,NA |
| Accuracy | NA,NA,NA |
| Peptide Atlas | NA |
| IEDB | |