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Details of CancerPDF entry with Sequence RIHWESASLLR
Primary information
sequence IDSeq_6579
Peptide sequenceRIHWESASLLR
CancerPDF_ID CancerPDF_ID936, CancerPDF_ID9464, CancerPDF_ID9600,
PMID19795908,26379225,21533267
Protein NameComplement C3,Complement C3,Complement C3
UniprotKB Entry NameCO3_HUMAN,CO3_HUMAN,CO3_HUMAN
FluidPlasma,Plasma,Serum
M/Z456.58,1367.77,456.58
Charge3,NA,3
Mass (in Da)NA,NA,NA
fdrNA,NA,NA
Profiling TechniqueLC-MS,MALDI-TOF,LC-MS
Peptide Identification techniqueMALDI-TOF/TOF,MALDI-TOF/TOF,LC/MS/MS
Quantification TechniqueLC-MRM (multiple reaction monitoring),NA,Multiple Reaction Monitoring
Labelled/Label FreeLabelled,Label Free,Label Free
FDRless than 7%,NA,1.49
CancerPDF_ID CancerPDF_ID936, CancerPDF_ID9464, CancerPDF_ID9600,
p-ValueNA,NA,NA
SoftwareFlexAnalysis 3.0 and Biotools 3.0 software,MASCOT (v 2.3),MASCOT
Length11,11,11
Cancer TypeDuctal adenocarcinoma of the pancreas (DAP),Colorectal cancer,Lung adenocarcinoma
DatabaseNCBI refseq Protein Database,UniprotKB,Swissprot Database (57.4)
ModificationNA,NA,NA
Number of Patients"42 normal, 28 patients","94 patients with CRC, 23 with liver metastasis from CRC (histologically defined) and 34 subjects, which underwent colonoscopy and resulted negative",62 lung adenocarcinoma and 30 healthy control
RegulationNA,Lower intensity in liver metastasis than control groups and an opposite trend in adenoma and CRC group.,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal"
ValidationNA,NA,MRM-based validation of 19 candidates
SensitivityNA,NA,NA
SpecificityNA,NA,NA
AccuracyNA,NA,NA
Peptide AtlasNA
IEDB533899