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Details of CancerPDF entry with Sequence NVHSGSTFFKYYLQGAKIPKPEAS
Primary information
sequence IDSeq_5821
Peptide sequenceNVHSGSTFFKYYLQGAKIPKPEAS
CancerPDF_ID CancerPDF_ID11058,
PMID26993605
Protein NameITIH4
UniprotKB Entry NameITIH4_HUMAN
FluidSerum
M/Z2669.1
Profiling TechniqueMALDI-TOF
Peptide Identification techniqueLTQ-Orbitrap-MS/MS
Labelled/Label FreeLabel Free
FDRless than 0.000008
CancerPDF_ID CancerPDF_ID11058,
p-Valueless than 0.05
SoftwareSEQUEST
Length24
Cancer TypeEsophageal squamous cell carcinoma (ESCC)
DatabaseIPI Human Database (3.45)
ModificationNA
Number of Patientsfor training 100 ESCC patients and 98 healthy individuals were used and for validation 101 ESCC patients and 98 healthy individuals were used
RegulationUpregulated in ESCC patients vs control with mean intensity in cancer 417.72 and mean intensity in normal 190.00
Validationexternal cross validation done
Sensitivity97% on training dataset and 97.3 on validation dataset
Specificity95.92% on training dataset and 100% on validation dataset
AccuracyNA
Peptide AtlasNA
IEDBNA