Primary information |
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sequence ID | Seq_5765 |
Peptide sequence | NRIPESGGDNSVFDIFELTGAARKGSGR |
CancerPDF_ID | CancerPDF_ID2154, CancerPDF_ID11051, |
PMID | 21136997,26993605 |
Protein Name | Thrombospondin-1,Thrombospondin-1 |
UniprotKB Entry Name | TSP1_HUMAN,TSP1_HUMAN |
Fluid | Serum,Serum |
M/Z | 2949.4693,2950.6 |
Charge | 1,NA |
Mass (in Da) | NA,NA |
fdr | NA,NA |
Profiling Technique | LC-MS,MALDI-TOF |
Peptide Identification technique | LC-MS-MS/MS,LTQ-Orbitrap-MS/MS |
Quantification Technique | LC-ESI-MS,NA |
Labelled/Label Free | Label Free,Label Free |
FDR | NA,less than 0.000001 |
CancerPDF_ID | CancerPDF_ID2154, CancerPDF_ID11051, |
p-Value | NA,less than 0.05 |
Software | MASCOT(v. 2.2.01),SEQUEST |
Length | 28,28 |
Cancer Type | Colorectal cancer,Esophageal squamous cell carcinoma (ESCC) |
Database | SwissProt Database,IPI Human Database (3.45) |
Modification | NA,NA |
Number of Patients | 30 patients and 30 healthy controls,for training 100 ESCC patients and 98 healthy individuals were used and for validation 101 ESCC patients and 98 healthy individuals were used |
Regulation | NA,Upregulated in patients vs normal with mean intensity 84.95 in control and 666.08 in cancer |
Validation | Leave One out Cross validation,external cross validation done |
Sensitivity | NA,97% on training dataset and 97.3 on validation dataset |
Specificity | NA,95.92% on training dataset and 100% on validation dataset |
Accuracy | NA,NA |
Peptide Atlas | NA |
IEDB | |