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Details of CancerPDF entry with Sequence LTKKFSRHHGPTITAKL
Primary information
sequence IDSeq_5211
Peptide sequenceLTKKFSRHHGPTITAKL
CancerPDF_ID CancerPDF_ID6096, CancerPDF_ID10385, CancerPDF_ID11057,
PMID24982608,21805675,26993605
Protein NameProtein AMBP,Protein AMBP,AMBP
UniprotKB Entry NameAMBP_HUMAN,AMBP_HUMAN,AMBP_HUMAN
FluidUrine,Urine,Serum
M/ZNA,1935.1239,1935.9
ChargeNA,NA,NA
Mass (in Da)NA,NA,NA
fdrNA,NA,NA
Profiling TechniqueNano-LC-MS,MALDI-TOF,MALDI-TOF
Peptide Identification techniqueMS/MS,MALDI-TOF-MS,LTQ-Orbitrap-MS/MS
Quantification TechniqueNA,NA,NA
Labelled/Label FreeLabel Free,Label Free,Label Free
FDR0.01,1,less than 0.000007
CancerPDF_ID CancerPDF_ID6096, CancerPDF_ID10385, CancerPDF_ID11057,
p-ValueNA,NA,less than 0.05
Software"GPM search engine, MASCOT",NA,SEQUEST
Length17,17,17
Cancer TypeOvarian cancer,Muscle-invasive bladder cancer,Esophageal squamous cell carcinoma (ESCC)
DatabaseIPI 3.71 Human Database ,SwissProt Database,IPI Human Database (3.45)
ModificationNA,NA,NA
Number of Patients6 Ovarian cancer patients and 6 normal individuals,751 bladder cancer and 127 control,for training 100 ESCC patients and 98 healthy individuals were used and for validation 101 ESCC patients and 98 healthy individuals were used
RegulationUniquely present in case of urine of ovarian cancer patients,Differentially expressed between cancer vs normal samples,"Downregulated in ESCC patients vs control with mean intensity in cancer 1018.23 and mean intensity in normal 2,456.36in normal"
ValidationNA,Mann-Whitney tests and areas under receiver-operator characteristic,external cross validation done
SensitivityNA,NA,97% on training dataset and 97.3 on validation dataset
SpecificityNA,NA,95.92% on training dataset and 100% on validation dataset
AccuracyNA,NA,NA
Peptide AtlasNA
IEDB