Primary information |
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sequence ID | Seq_5211 |
Peptide sequence | LTKKFSRHHGPTITAKL |
CancerPDF_ID | CancerPDF_ID6096, CancerPDF_ID10385, CancerPDF_ID11057, |
PMID | 24982608,21805675,26993605 |
Protein Name | Protein AMBP,Protein AMBP,AMBP |
UniprotKB Entry Name | AMBP_HUMAN,AMBP_HUMAN,AMBP_HUMAN |
Fluid | Urine,Urine,Serum |
M/Z | NA,1935.1239,1935.9 |
Charge | NA,NA,NA |
Mass (in Da) | NA,NA,NA |
fdr | NA,NA,NA |
Profiling Technique | Nano-LC-MS,MALDI-TOF,MALDI-TOF |
Peptide Identification technique | MS/MS,MALDI-TOF-MS,LTQ-Orbitrap-MS/MS |
Quantification Technique | NA,NA,NA |
Labelled/Label Free | Label Free,Label Free,Label Free |
FDR | 0.01,1,less than 0.000007 |
CancerPDF_ID | CancerPDF_ID6096, CancerPDF_ID10385, CancerPDF_ID11057, |
p-Value | NA,NA,less than 0.05 |
Software | "GPM search engine, MASCOT",NA,SEQUEST |
Length | 17,17,17 |
Cancer Type | Ovarian cancer,Muscle-invasive bladder cancer,Esophageal squamous cell carcinoma (ESCC) |
Database | IPI 3.71 Human Database ,SwissProt Database,IPI Human Database (3.45) |
Modification | NA,NA,NA |
Number of Patients | 6 Ovarian cancer patients and 6 normal individuals,751 bladder cancer and 127 control,for training 100 ESCC patients and 98 healthy individuals were used and for validation 101 ESCC patients and 98 healthy individuals were used |
Regulation | Uniquely present in case of urine of ovarian cancer patients,Differentially expressed between cancer vs normal samples,"Downregulated in ESCC patients vs control with mean intensity in cancer 1018.23 and mean intensity in normal 2,456.36in normal" |
Validation | NA,Mann-Whitney tests and areas under receiver-operator characteristic,external cross validation done |
Sensitivity | NA,NA,97% on training dataset and 97.3 on validation dataset |
Specificity | NA,NA,95.92% on training dataset and 100% on validation dataset |
Accuracy | NA,NA,NA |
Peptide Atlas | NA |
IEDB | |