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Details of CancerPDF entry with Sequence LSALEEYTKKLNTQ
Primary information
sequence IDSeq_5123
Peptide sequenceLSALEEYTKKLNTQ
CancerPDF_ID CancerPDF_ID73, CancerPDF_ID3615, CancerPDF_ID6048, CancerPDF_ID10239,
PMID16896061,27026199,24982608,21805675
Protein NameApolipoprotein A-I,Apolipoprotein A-I,Apolipoprotein A-I,Apolipoprotein A-I
UniprotKB Entry NameAPOA1_HUMAN,APOA1_HUMAN,APOA1_HUMAN,APOA1_HUMAN
FluidSerum,Urine,Urine,Urine
M/Z819.35,NA,NA,1637.8575
Charge1,NA,NA,NA
Mass (in Da)1637.87,NA,NA,NA
fdrNA,1636.85,NA,NA
Profiling TechniqueMALDI-TOF,"CE-MS, Micro-TOF-MS",Nano-LC-MS,MALDI-TOF
Peptide Identification techniqueQ/TOF MS/MS,MS-MS,MS/MS,MALDI-TOF-MS
Quantification TechniqueNA,NA,NA,NA
Labelled/Label FreeLabel Free,Label Free,Label Free,Label Free
FDRNA,NA,0.01,1
CancerPDF_ID CancerPDF_ID73, CancerPDF_ID3615, CancerPDF_ID6048, CancerPDF_ID10239,
p-Value1.00E-05,less than 0.01,NA,NA
SoftwareMASCOT,Proteome Discoverer 1.2,"GPM search engine, MASCOT",NA
Length14,14,14,14
Cancer TypeMetastatic thyroid carcinomas,Bladder cancer,Ovarian cancer,Muscle-invasive bladder cancer
DatabaseNCBI refseq Protein Database,Uniprot Human non-redundant Database,IPI 3.71 Human Database ,SwissProt Database
ModificationNA,NA,NA,NA
Number of Patients40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation, 425 for training(109 patients with Recurrent UBC cases and 316 negative for recurrence controls) and 211 for validation (55 UBC recurrent cases and 156 recurrent controls),6 Ovarian cancer patients and 6 normal individuals,751 bladder cancer and 127 control
RegulationNA,Differentially expressed between recurrence of UBC vs recurrence control,Uniquely present in case of urine of ovarian cancer patients,Differentially expressed between cancer vs normal samples
ValidationIndependent validation,Independent Validation,NA,Mann-Whitney tests and areas under receiver-operator characteristic
Sensitivity95% on independent dataset,For testing dataset 88%,NA,NA
Specificity95% on independent dataset,For testing dataset 51%,NA,NA
AccuracyNA,NA,NA,NA
Peptide AtlasNA
IEDB120086