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Details of CancerPDF entry with Sequence LAPLAEDVRGNL
Primary information
sequence IDSeq_4588
Peptide sequenceLAPLAEDVRGNL
CancerPDF_ID CancerPDF_ID79, CancerPDF_ID360, CancerPDF_ID1375, CancerPDF_ID2579, CancerPDF_ID9571,
PMID16896061,19795908,21136997,21136997,21533267
Protein NameApolipoprotein A-IV,Apolipoprotein A-IV,Apolipoprotein A-IV,Apolipoprotein A-IV,Apolipoprotein A-IV
UniprotKB Entry NameAPOA4_HUMAN,APOA4_HUMAN,APOA4_HUMAN,APOA4_HUMAN,APOA4_HUMAN
FluidSerum,Plasma,Serum,Plasma,Serum
M/Z634.29,634.35,1266.6932,1266.6932,634.35
Charge2,2,1,1,2
Mass (in Da)1267.69,NA,NA,NA,NA
fdrNA,NA,NA,NA,NA
Profiling TechniqueMALDI-TOF,LC-MS,LC-MS,LC-MS,LC-MS
Peptide Identification techniqueQ/TOF MS/MS,MALDI-TOF/TOF,LC-MS-MS/MS,LC-MS-MS/MS,LC/MS/MS
Quantification TechniqueNA,LC-MRM (multiple reaction monitoring),LC-ESI-MS,LC-ESI-MS,Multiple Reaction Monitoring
Labelled/Label FreeLabel Free,Labelled,Label Free,Label Free,Label Free
FDRNA,less than 7%,NA,NA,1.49
CancerPDF_ID CancerPDF_ID79, CancerPDF_ID360, CancerPDF_ID1375, CancerPDF_ID2579, CancerPDF_ID9571,
p-Value1.00E-05,NA,NA,NA,NA
SoftwareMASCOT,FlexAnalysis 3.0 and Biotools 3.0 software,MASCOT(v. 2.2.01),MASCOT(v. 2.2.01),MASCOT
Length12,12,12,12,12
Cancer TypeMetastatic thyroid carcinomas,Ductal adenocarcinoma of the pancreas (DAP),Colorectal cancer,Normal,Lung adenocarcinoma
DatabaseNCBI refseq Protein Database,NCBI refseq Protein Database,SwissProt Database,SwissProt Database,Swissprot Database (57.4)
ModificationNA,NA,NA,NA,NA
Number of Patients40 metastatic thyroid carcinoma patients and 40 normal for training phase and 10 metastatic thyroid carcinoma and 10 normal individuals for independent validation,"40 normal, 28 patients",30 patients and 30 healthy controls,27 healthy individuals,62 lung adenocarcinoma and 30 healthy control
RegulationNA,NA,NA,NA,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal"
ValidationIndependent validation,NA,Leave One out Cross validation,Leave One out Cross validation,MRM-based validation of 19 candidates
Sensitivity95% on independent dataset,NA,NA,NA,NA
Specificity95% on independent dataset,NA,NA,NA,NA
AccuracyNA,NA,NA,NA,NA
Peptide AtlasPeptideAtlas
IEDB