| Primary information |
|---|
| sequence ID | Seq_4281 |
| Peptide sequence | KMADEAGSEADHEGTHSTKRGHAKSRPV |
| CancerPDF_ID | CancerPDF_ID8529, CancerPDF_ID9708, CancerPDF_ID12727, |
| PMID | 23667664,21533267,27058005 |
| Protein Name | Fibrinogen alpha,Fibrinogen alpha chain,Fibrinogen alpha chain |
| UniprotKB Entry Name | FIBA_HUMAN,FIBA_HUMAN,FIBA_HUMAN |
| Fluid | Serum,Serum,Serum |
| M/Z | 2988.42,748.1,3005.608 |
| Charge | 1,4,NA |
| Mass (in Da) | 2991.23,NA,NA |
| fdr | NA,NA,NA |
| Profiling Technique | MALDI-TOF,LC-MS,MALDI-TOF |
| Peptide Identification technique | FT-ICR MS/MS + nano-HPLC,LC/MS/MS,LC-MS/MS |
| Quantification Technique | NA,Multiple Reaction Monitoring,NA |
| Labelled/Label Free | Label Free,Label Free,Label Free |
| FDR | NA,1.49,NA |
| CancerPDF_ID | CancerPDF_ID8529, CancerPDF_ID9708, CancerPDF_ID12727, |
| p-Value | NA,NA,"0.096,less than 0.05,0.059" |
| Software | MASCOT,MASCOT,Proteome Discoverer |
| Length | 28,28,28 |
| Cancer Type | "Breast cancer, Lung cancer, Rectal cancer",Lung adenocarcinoma,Breast cancer |
| Database | NA,Swissprot Database (57.4),SwissProt Database |
| Modification | NA,NA,Oxidation (M) |
| Number of Patients | "Breast Cancer =84, lung cancer= 70, Rectal cancer = 30patients; 500 healthy",62 lung adenocarcinoma and 30 healthy control," 28 were diagnosed with Breast cancer, 27 remained cancer-free with BRCA carrier. Of the remaining patients, 39 were diagnosed with sporadic breast cancer (SBC), and 38 were healthy volunteers (WT)." |
| Regulation | NA,"Differentially expressed between earlier-stage lung cancer group (stage-I, II, and IIIa) vs normal","Upregulated with the fold change of 1.73 in breast cancer vs Cancer free patients with brca mutation, Upregulated in breast cancer vs sporadic breast cancer with fold change of 2.39, Upregulated in BC vs healthy with 2.324 fold change" |
| Validation | NA,MRM-based validation of 19 candidates,NA |
| Sensitivity | NA,NA,NA |
| Specificity | NA,NA,NA |
| Accuracy | NA,NA,NA |
| Peptide Atlas | NA |
| IEDB | |